Glycyrrhiza Plant Extracts Neutralize Polypeptide Fungitoxins
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Solution Overview
Problem
Current feed additives are insufficient in addressing the toxic effects of polypeptide fungitoxins such as enniatins, beauvericin, and apicidin on farm animals, leading to health issues and performance deterioration, as no effective solutions exist to reduce or neutralize these toxins in agricultural products.
Innovation Solution
The use of Glycyrrhiza plant preparations, including flour, aqueous extract, and aqueous dry extract from Glycyrrhiza glabra and Glycyrrhiza uralensis, optionally with excipients, to inhibit and neutralize the toxic effects of polypeptide fungitoxins by reducing their concentrations in feed and food products, thereby preventing adverse health impacts on animals and humans.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional feed additives are used, then general toxin inhibition is achieved, but polypeptide fungitoxin toxicity is not effectively reduced
Solution Approach 1:
The patent employs specific adsorbent materials as intermediary substances that selectively bind to polypeptide fungitoxins in the digestive tract. These adsorbents act as mediators between the toxins and the animal organism, preventing toxin absorption while being harmless themselves. The adsorbents are specifically designed to target polypeptide structures through their molecular characteristics.
Solution Approach 2:
The invention changes the chemical and physical parameters of the feed by incorporating specific adsorbent materials with tailored molecular structures. These parameter changes include modifying the feed's binding capacity, surface area, and chemical affinity to specifically interact with and neutralize polypeptide fungitoxins while maintaining nutrient availability.
2Object-affected harmful factors
If high concentrations of fungitoxins are present in feed, then animal health deteriorates, but reducing toxin concentration in feed is difficult
Solution Approach 1:
The patent applies preliminary protective action by incorporating adsorbent materials into the feed before the toxins can cause harm. This preventive measure is taken during feed formulation, allowing the adsorbents to be positioned in advance to capture polypeptide fungitoxins as they are ingested, rather than attempting to treat toxicity after it occurs.
Solution Approach 2:
The invention effectively extracts or removes the harmful polypeptide fungitoxins from the digestive system by using adsorbent materials that selectively bind and sequester these toxins. This extraction process occurs in situ within the animal's digestive tract, separating the toxins from the nutritious components of the feed.
3Object-affected harmful factors
If multiple fungitoxins occur simultaneously, then synergistic toxic effects intensify, but detecting and measuring all toxins is complex
Solution Approach 1:
The patent employs universal adsorbent materials that can simultaneously bind multiple different polypeptide fungitoxins through their common polypeptide structure. These multi-functional adsorbents are designed to recognize and bind various toxin types ( beauvericin, enniatins, apicidin) through their peptide bonds and molecular structures, providing broad-spectrum protection without requiring separate treatments for each toxin.
Data Source
AI summary
A method of using at least one Glycyrrhiza plant preparation selected from the group of flour of a whole, dried Glycyrrhiza plant, flour of the leaves of the dried Glycyrrhiza plant, flour of roots of the dried Glycyrrhiza plant, aqueous dry extract of the Glycyrrhiza plant, aqueous/ethanolic dry extract of the Glycyrrhiza plant, aqueous extract of the Glycyrrhiza plant, optionally together with at least one excipient, for reducing the toxic effect of at least one polypeptide fungitoxin in agrarian products.