GPVE Extract for Skin Protection Against UV Damage
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Solution Overview
Problem
Current cosmetic and dermatological preparations are inadequate in effectively protecting the skin against extrinsic skin aging caused by external factors such as UV light, chemical reagents, mechanical stress, cigarette smoke, and air pollution, which leads to wrinkling, loss of elasticity, and dry skin appearance.
Innovation Solution
A combination of glycoprotein 1 from the purified cytoplasmatic fraction of yeasts (Saccharomyces), glycoprotein 2 from the purified cytoplasmatic fraction of Lactobacillus, ginseng extract, and horsetail extract, referred to as GPVE extract, is used in cosmetic or dermatological preparations to protect the skin against extrinsic aging. This combination is produced through biotechnological means and can be formulated into various skin care products, including creams, lotions, and serums, with optional additives like glycerol, sodium dehydroacetate, phenoxyethanol, potassium sorbate, and ethylhexylglycerol.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cosmetic preparations are used, then basic skin care is provided, but protection against extrinsic skin aging is insufficient
Solution Approach 1:
The patent combines four distinct active ingredients (glycoprotein 1, glycoprotein 2, ginseng extract, and horsetail extract) into a composite formulation. Each component contributes different protective mechanisms: glycoproteins provide antioxidant protection, ginseng extract enhances cellular repair, and horsetail extract provides additional antioxidant support. This composite approach creates synergistic effects that significantly improve protection against UV damage and oxidative stress compared to single-ingredient preparations.
Solution Approach 2:
The patent optimizes the concentration and formulation parameters of each active ingredient to maximize protective efficacy. By carefully controlling the composition ratios and processing conditions during manufacturing, the formulation achieves enhanced stability and bioavailability, thereby improving its ability to protect skin cells from extrinsic aging factors.
2Reliability
If skin protection against extrinsic aging is enhanced, then skin health is improved, but the complexity of the preparation increases
Solution Approach 1:
The complex protective function is divided into multiple specialized components, each targeting specific aspects of extrinsic aging. Glycoprotein 1 and glycoprotein 2 address antioxidant protection, ginseng extract focuses on cellular regeneration, and horsetail extract provides additional protective mechanisms. This segmentation allows each ingredient to be optimized for its specific function while working together in a coordinated manner.
Solution Approach 2:
The composite formulation is designed to provide multiple protective functions simultaneously: antioxidant protection, anti-inflammatory effects, cellular regeneration, and UV damage mitigation. This multi-functionality reduces the need for separate products targeting different aging concerns, thereby managing formulation complexity while delivering comprehensive skin protection.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The GPVE extract significantly reduces UV-induced damage to mitochondrial DNA by approximately 90%, protects epidermal and dermal stem cells from oxidative stress, and stimulates the synthesis of essential skin lipids, thereby effectively preventing skin aging and maintaining skin health and elasticity.
Implementation Method 1
The GPVE extract significantly reduces UV-induced damage to mitochondrial DNA by approximately 90%, protects epidermal and dermal stem cells from oxidative stress
Implementation Method 2
The extract comprising b), c) and d), referred to as VE extract, and can be obtained by a multistage biotechnological process using Lactobacillus casei. Lactobacillus casei, which are particularly rich in lytic enzymes, are transferred to a fermentation culture medium where they are able to grow.
Data Source
AI summary
The invention is a cosmetic or dermatological preparation and the use thereof, said preparation comprising a combination of a) glycoprotein 1, b) glycoprotein 2, ginseng extract and d) equisetum extract, to protect the skin against extrinsic skin aging.