Gradient Protein Film for Dual Antioxidant and Antimicrobial Release

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Solution Overview

Problem

Protein-based edible films face limitations in mechanical performance and moisture resistance, making it difficult to achieve simultaneous long-term oxidation resistance and antimicrobial properties due to poor compatibility between water-soluble antioxidants and lipid-soluble antimicrobial agents.

Innovation Solution

A gradient slow-release active composite film is developed, comprising an antioxidative hygroscopic internal layer, a gradient anti-microbial antioxidative intermediate layer, and a waterproof external layer, where lipid-soluble plant essential oil and water-soluble antioxidants are combined with an alcohol-soluble protein-water-soluble protein substrate, allowing for simultaneous long-term oxidation resistance and antimicrobial properties, excellent moisture resistance, and good mechanical performance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If water-soluble antioxidants and lipid-soluble antimicrobial agents are loaded separately to different substrates, then compatibility is improved, but the film can only provide single function (either antioxidant or antimicrobial) with short duration

Engineering Contradiction:
Improvecompatibility of active substancesVSAvoidsimultaneous antioxidant and antimicrobial function
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent merges water-soluble antioxidants and lipid-soluble antimicrobial agents into a single film system by using a multi-layer composite structure where both active substances are incorporated together, enabling simultaneous antioxidant and antimicrobial functions with extended duration

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs a composite film structure combining hydrophilic and hydrophobic layers, allowing different active substances to be loaded into appropriate layers based on their solubility characteristics, achieving both compatibility and multi-functionality

Inventive Principle:
Principle #40Composite materials

2Strength

If protein-based films are used as edible packaging, then air permeability and mechanical properties are improved, but moisture resistance deteriorates

Engineering Contradiction:
Improvemechanical performanceVSAvoidmoisture resistance
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The patent creates a composite film system combining hydrophilic protein layers (providing mechanical strength and air permeability) with hydrophobic layers (providing moisture resistance), where each layer contributes its advantageous properties to the overall film performance

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent divides the film into multiple functional layers with distinct properties - hydrophilic layers for mechanical performance and hydrophobic layers for moisture barrier, allowing each segment to optimize its specific function

Inventive Principle:
Principle #1Segmentation

3Device complexity

If single-layer edible films are used, then simplicity of structure is maintained, but simultaneous achievement of oxidation resistance and antimicrobial property with long duration is difficult

Engineering Contradiction:
Improvefilm structure complexityVSAvoidduration of antioxidant and antimicrobial effect
Core Design Contradiction:
Device complexityVSDuration of action of moving object

Solution Approach 1:

The patent divides the film into multiple layers with specific functions - hydrophilic internal layers for antioxidant loading, hydrophobic external layers for antimicrobial agent loading, and intermediate transition layers for mechanical adjustment - enabling long-term dual functionality through functional segmentation

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses composite multi-layer structure combining different protein matrices and active substances, where each layer is optimized for specific functions, achieving extended duration of both antioxidant and antimicrobial effects simultaneously

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The film achieves long-term oxidation resistance and antimicrobial properties, excellent moisture resistance, and good mechanical performance, with improved retention rates of active substances and encapsulation for controlled release, suitable for food packaging applications.

Implementation Method 1

a hydrophobic external layer, a mechanical property-adjustable intermediate transition layer and a hydrophilic internal layer

Methodology Applied
Scientific EffectHydrophobic effect: Hydrophobe

Implementation Method 2

a hydrophobic external layer, a mechanical property-adjustable intermediate transition layer and a hydrophilic internal layer

Methodology Applied
Scientific EffectHydrophilic effect: Hydrophile

Implementation Method 3

gradient slow-release active composite film

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentUS12060208B2Gradient slow-release active composite film and preparation method thereof
Publication Date: 2024.08.13 SOUTH CHINA AGRICULTURAL UNIVERSITY
  • US12060208B2 patent drawing

AI summary

The present invention discloses a gradient slow-release active composite film and a preparation method thereof. The active composite film, from inside to outside, is composed of an antioxidative hygroscopic internal layer, at least one gradient anti-microbial antioxidative intermediate layer and at least one waterproof external layer; wherein the antioxidative hygroscopic internal layer is prepared by an alcohol-soluble protein-water-soluble protein substrate and a water-soluble antioxidant; the gradient anti-microbial antioxidative intermediate layer is prepared by an alcohol-soluble protein-water-soluble protein substrate and a lipid-soluble plant essential oil and a water-soluble antioxidant, wherein a mass ratio of the alcohol-soluble protein to the water-soluble protein is (1-2):(1-2); and the waterproof external layer is composed of a hydrophobic alcohol-soluble protein layer.