Graphene Biosensor Cartridge for Accurate Multi-Channel Detection
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Solution Overview
Problem
Existing biosensors face challenges in accuracy and user-friendliness, particularly in visually determining color changes for target material concentration, and stability and reaction reliability when directly attached to the human body.
Innovation Solution
A biosensor cartridge with a biosensor chip featuring a graphene channel and transistor structure, allowing multiple channels for simultaneous detection of target materials, and a portable diagnostic device for reading electrical signals, ensuring accuracy and reliability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a strip-type rapid kit with color development is used for target material detection, then the device is simple and easy to use, but the accuracy of concentration determination is poor and difficult to distinguish for laypersons
Solution Approach 1:
The patent replaces the visual color development system with an electrochemical detection system using a graphene-based biosensor. The biosensor converts the biochemical reaction between probe material and target material into an electrical signal (current change), which is then processed and displayed numerically. This substitution of visual assessment with electrical measurement eliminates subjectivity and improves measurement precision while maintaining ease of operation through automated signal processing.
2Ease of operation
If a graphene-based biosensor is directly attached to the human body for detection, then the device is portable and simple, but the stability and reaction reliability are poor
Solution Approach 1:
The patent divides the biosensor system into separate functional modules: the graphene-based biosensor chip containing multiple channel areas with probe materials, a holder for stable mounting, and a separate processing unit for signal amplification and analysis. This segmentation allows the biosensor to be portable while the modular architecture ensures stable connections and reliable reactions by preventing contamination and maintaining proper positioning of sensitive components.
3Productivity
If multiple channel areas with different probe materials are integrated in a single biosensor chip, then the productivity and detection capability are improved, but the device complexity increases
Solution Approach 1:
The patent designs a universal biosensor chip platform with multiple channel areas that can accommodate different probe materials for detecting various target materials. Each channel follows the same structural pattern (graphene electrode with probe material attachment), allowing the chip to perform multiple detection functions simultaneously. This multi-functional design increases productivity by enabling parallel detection of multiple analytes while managing complexity through standardized modular channel structures.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The biosensor cartridge enables accurate, reliable, and rapid detection of multiple target materials with electrical signals, improving user-friendliness and stability, suitable for portable diagnostics.
Implementation Method 1
when a target material is combined in a channel, if an electrochemical reaction occurs or the target material itself has a charge, electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect caused by the combination of the probe material and the target material
Implementation Method 2
electrons or holes in the semiconductor structure are accumulated or depleted due to the electric field effect caused by the combination of the probe material and the target material
Data Source
AI summary
A biosensor cartridge can include a circuit board having a connection terminal configured to be electrically connected to an external diagnostic device, a biosensor chip configured to detect a target material from an analysis specimen, and transmit an electrical signal to the connection terminal of the circuit board based on the target material being present in the analysis specimen, the biosensor chip including a reactant configured to react specifically with the target material, and a housing enclosing the circuit board and the biosensor chip, and the connecting terminal being exposed outside of the housing. Also, the biosensor chip includes a plurality of channel areas separated from each other, and the reactant is attached to the plurality of channel areas.