GRAS Polymer Antimicrobial Composition for Lower Processing Temperatures

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Solution Overview

Problem

High-performance thermoplastics like acetal and TPU are susceptible to acid hydrolysis and depolymerization when using acidic additives, necessitating an alternative microbial control method that maintains their properties while avoiding processing issues.

Innovation Solution

A composition comprising a Generally-Recognized-as-Safe (GRAS) additive, such as organic acids like benzoic acid and 3-phenylpropanol, is used in a synergistic ratio to provide antimicrobial protection, reducing processing temperatures and forming a compounded material for molding.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If acidic additives are used for microbial control in high-performance thermoplastics, then antimicrobial protection is improved, but polymer stability deteriorates due to acid hydrolysis and depolymerization

Engineering Contradiction:
Improvemicrobial controlVSAvoidpolymer stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent changes the chemical parameters of the antimicrobial additive by using GRAS substances (organic acids like benzoic acid, sorbic acid, citric acid) instead of traditional strong acids. This parameter change maintains antimicrobial efficacy while reducing the harmful acidic effects that cause polymer degradation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite antimicrobial system by combining GRAS organic acids with phenylpropanol or phenylpropanoid derivatives. This composite approach provides synergistic antimicrobial protection while both components are safe for use with sensitive polymers like acetal and TPU.

Inventive Principle:
Principle #40Composite materials

2Reliability

If high levels of antimicrobial additives are used to ensure effective microbial control, then antimicrobial efficacy is improved, but processing temperature increases

Engineering Contradiction:
Improvemicrobial controlVSAvoidprocessing temperature
Core Design Contradiction:
ReliabilityVSTemperature

Solution Approach 1:

The patent optimizes the concentration parameters of antimicrobial additives by using synergistic combinations at lower levels. The GRAS organic acid combined with phenylpropanol achieves enhanced antimicrobial efficacy at reduced additive concentrations, thereby lowering processing temperatures.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent merges two antimicrobial components (GRAS organic acid and phenylpropanol/phenylpropanoid) into a single additive system that provides synergistic effects. This combination allows effective microbial control at lower overall additive levels compared to using single high-concentration additives.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The synergistic effect of GRAS additives and 3-phenylpropanol achieves effective microbial control with reduced additive levels, stabilizing the processing temperature and maintaining the integrity of high-performance thermoplastics.

Implementation Method 1

The composition exhibits a synergistic antimicrobial effect

Methodology Applied
Scientific EffectSynergistic antimicrobial effect:

Implementation Method 2

adding 3-phenylpropanol or a member of the phenylpropanoid family into a thermoplastic polymer thereby reducing the processing temperature of the thermoplastic polymer

Methodology Applied
Scientific EffectProcessing temperature reduction:

Data Source

PatentUS12378388B2Composition and method for microbial control for use with polymers
Publication Date: 2025.08.05 MICROBAN PROD CO INC

AI summary

A composition having an additive or component having an antimicrobial or a preservative property, and 3-phenylpropanol or a member of the phenylpropanoid family is provided. A composition having a polymer, an organic acid, and 3-phenylpropanol or a member of the phenylpropanoid family is provided as well as a method(s) of using.