Grating Interferometer Contrast and Resolution via CNN

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Solution Overview

Problem

Grating interferometers face challenges in simultaneously achieving high contrast sensitivity and spatial resolution, making it difficult to acquire images with both high sensitivity and resolution.

Innovation Solution

The use of a machine learning-based system that includes a grating interferometer image acquisition unit, a numerical phantom generation unit, a convolution layer generation unit, an activation function application calculation unit, a CNN repetitive machine learning unit, and an image matching output unit to enhance contrast sensitivity and resolution.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a grating interferometer is used to achieve high contrast sensitivity, then the ability to detect subtle variations in the sample is improved, but the spatial resolution deteriorates

Engineering Contradiction:
Improvecontrast sensitivityVSAvoidspatial resolution
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The patent segments the imaging process into multiple measurements taken at different sample positions relative to the grating interferometer. By acquiring images at multiple positions and combining them through machine learning, the system achieves both high contrast sensitivity and high spatial resolution that cannot be obtained at any single position alone.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a new dimension by adding the sample position parameter to the imaging process. Instead of relying on a single imaging configuration, the system varies the sample position relative to the grating interferometer and uses machine learning to synthesize information across this additional dimensional parameter, thereby resolving the contradiction between contrast sensitivity and spatial resolution.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If machine learning processing is applied to enhance image quality, then contrast sensitivity and resolution are improved, but computational complexity and processing time increase

Engineering Contradiction:
Improveimage qualityVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by performing machine learning training offline to create a pre-trained model. Once trained, the model can be deployed for rapid inference on new images without requiring complex real-time computation during actual imaging, thus reducing the computational burden during operational use.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the improvement of both contrast sensitivity and spatial resolution in grating interferometers, enabling the extraction of high-quality image information with enhanced sensitivity and resolution.

Implementation Method 1

phase-contrast imaging using a grating interferometer in which an interference principle is applied to radiation

Methodology Applied
Scientific EffectInterference: Interference

Data Source

PatentUS12266162B2Enhancing contrast sensitivity and resolution in a grating interferometer by machine learning
Publication Date: 2025.04.01 RENESSELAER POLYTECHNIC INST
  • US12266162B2 patent drawing
  • US12266162B2 patent drawing
  • US12266162B2 patent drawing

AI summary

The present disclosure relates to an apparatus for enhancing contrast sensitivity and resolution in a grating interferometer by machine learning, which can improve both image contrast sensitivity and spatial resolution in a grating interferometer by machine learning, the apparatus including: an image acquisition unit; a numerical phantom generation unit, a convolution layer generation unit to extract features from input data; an activation function application calculation unit that can apply a rectified linear activation function to an output value of the convolution calculation to perform smooth repetitive machine learning; a CNN repetitive machine learning unit that corrects a convolution calculation factor while repeatedly performing forward propagation and backward propagation processes; and an image matching output unit that matches and outputs features extracted by repetitive machine learning of the CNN repetitive machine learning unit.