Grating-Based X-Ray Phase Contrast Imaging Simulation

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Solution Overview

Problem

Current computer simulation tools are inefficient and inaccurate for simulating grating-based X-ray phase contrast imaging systems, particularly in CT applications, due to complex calculations and high computational requirements, which hinder the adaptation of this technology into clinical practice.

Innovation Solution

A computer simulation tool that decomposes virtual objects into absorption, phase, and small-angle scattering objects, separately modeling changes to the interference pattern attributed to each, allowing for efficient simulation of X-ray phase contrast imaging systems by aggregating these changes to generate a final interference pattern, thereby reducing processing time and resources.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If complex calculations are performed to accurately simulate X-ray phase contrast imaging systems, then measurement precision is improved, but productivity deteriorates due to lengthy processing time

Engineering Contradiction:
Improvesimulation accuracyVSAvoidprocessing speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The simulation process is divided into separate components: decomposition of virtual objects into sub-objects with different physical properties, separate modeling of absorption changes, phase changes, and dark field changes, and combination of results. This segmentation allows each component to be processed independently and efficiently, reducing overall computation time while maintaining accuracy.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system pre-calculates and stores the baseline interference pattern before processing individual objects. This preliminary action eliminates the need to recalculate the complete interference pattern for each object, significantly reducing processing time while preserving simulation accuracy.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If detailed and realistic digital representations of patients are used in simulations, then measurement precision is improved, but device complexity worsens due to high computational requirements

Engineering Contradiction:
Improvesimulation realismVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Virtual patient objects are decomposed into sub-objects representing different physical properties (absorption, phase, scattering). This segmentation allows realistic patient representations to be processed through separate, optimized computational pathways, reducing overall system complexity while maintaining realism.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The simulation system processes different physical properties as separate parameters (absorption coefficient, phase shift, scattering coefficient) rather than as a single complex object property. This parameterization simplifies the computational model while enabling detailed and realistic patient representations.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly reduces processing time and computational resources, enabling efficient simulation of X-ray phase contrast projections in CT imaging and facilitating the development and testing of new image generation algorithms, allowing for cost-effective implementation in clinical practice.

Implementation Method 1

a decomposition component that decomposes a virtual object into different sub-objects associated with different physical properties

Methodology Applied
Scientific EffectDecomposition:

Implementation Method 2

a phase change (e.g., a shift in the interference pattern at respective detector elements/pixels) attributed to the phase object

Methodology Applied
Scientific EffectPhase shift:

Implementation Method 3

a dark field change (e.g., a decrease in visibility and/or shape of the interference pattern at respective detector elements/pixels) attributed to the small-angle scattering object

Methodology Applied
Scientific EffectSmall-angle scattering: Scattering

Data Source

PatentUS20240265166A1Grating-based x-ray phase contrast imaging system simulation
Publication Date: 2024.08.08 GE PRECISION HEALTHCARE LLC
  • US20240265166A1 patent drawing
  • US20240265166A1 patent drawing
  • US20240265166A1 patent drawing

AI summary

Computer processing techniques are described for simulating grating-based X-ray phase contrast imaging systems. According to an example, a system comprises a memory that stores computer-executable components and a processor that executes the computer-executable components stored in the memory. The computer-executable components comprise a simulation component that simulates performance of an X-ray phase contrast imaging system using a simulation model, wherein the simulation model comprises a decomposition component that decomposes a virtual object into different sub-objects associated with different physical properties, and a projector component that separately models different changes to a baseline interference pattern received at a detector of the X-ray phase contrast imaging system respectively attributed to the different sub-objects in association with simulated projection of an X-ray beam through the different sub-objects.