Gravity-Driven Blood Filter with Venturi Region

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Solution Overview

Problem

Conventional blood reinfusion systems damage erythrocytes, result in significant blood component loss, are complex, difficult to operate, and not suitable for emergency or sterile environments, making them economically infeasible for many medical procedures.

Innovation Solution

A blood reinfusion system featuring a gravity-driven blood filtering system with a venturi region and multiple filters, designed to minimize shear forces and retain native blood components, allowing for efficient processing and reinfusion of autologous blood with minimal loss and damage, and can be operated manually by a single operator in sterile conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional blood reinfusion systems use centrifugation to separate blood components, then blood can be processed and reinfused, but erythrocytes are damaged and blood components are lost

Engineering Contradiction:
Improveblood processing efficiencyVSAvoiderythrocyte integrity
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent removes the centrifugation step entirely from the blood processing system. Instead of using centrifugal force to separate blood components, the system directly filters and reinfuses whole blood, extracting only the necessary impurities while preserving all blood components including erythrocytes, platelets, white blood cells, plasma proteins, and antibodies.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a filter as an intermediary component between blood collection and reinfusion. This filter selectively removes impurities (debris, clots, contaminants) while allowing all blood components to pass through intact, serving as a mediator that achieves purification without the harmful effects of centrifugation.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If conventional blood reinfusion systems use centrifugation to isolate erythrocytes, then blood can be processed, but platelets, white blood cells, plasma proteins and antibodies are discarded as waste

Engineering Contradiction:
Improveblood processing capabilityVSAvoidblood component retention
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The patent extracts only the harmful impurities from the blood while leaving all beneficial blood components intact. The filter is designed to remove debris, clots, and contaminants without separating or discarding platelets, white blood cells, plasma proteins, or antibodies, thereby preserving the complete blood component profile.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent recovers all blood components including platelets, white blood cells, plasma proteins, and antibodies that would otherwise be discarded. By using filtration instead of centrifugation, the system retains these valuable components in the reinfused blood, maximizing the therapeutic benefit.

Inventive Principle:
Principle #34Discarding and recovering

3Productivity

If conventional blood reinfusion systems use complex equipment with multiple specialized technicians, then blood processing can be performed, but the system is difficult to operate and requires advanced planning

Engineering Contradiction:
Improveblood processing functionVSAvoidsystem operability
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The patent segments the complex centrifugation-based system into a simple filtration-based system. By dividing the processing function into a single filtration step rather than multiple centrifugation and separation steps, the system becomes easier to operate and requires fewer specialized technicians while maintaining blood processing capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent creates a simplified version of blood processing that copies only the essential function (purification and reinfusion) without copying the complex centrifugation machinery. This simplified system achieves the same therapeutic goal with minimal equipment and operational complexity.

Inventive Principle:
Principle #26Copying

4Productivity

If conventional blood reinfusion systems are designed for non-emergency use, then complex processing can be performed, but the system is not suitable for emergency or sterile environments

Engineering Contradiction:
Improveblood processing capabilityVSAvoidenvironmental adaptability
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent changes the operational parameters of blood processing from complex, multi-step centrifugation to simple, rapid filtration. This parameter change enables the system to function effectively in emergency situations and sterile environments where time is critical and equipment simplicity is essential, while maintaining blood processing capability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively processes autologous blood with minimal damage to erythrocytes and retention of native components, reducing blood component loss and enabling efficient reinfusion, while being simple to use and adaptable for emergency and sterile environment applications.

Implementation Method 1

The internal fluid passageway comprises a venturi region, the venturi region comprising an inlet region, a restricted flow path region and an outlet region

Methodology Applied
Scientific EffectVenturi effect: Venturi Effect

Implementation Method 2

a gravity-driven blood filtering system adapted to extract impurities from the blood

Methodology Applied
Scientific EffectGravity: Gravitation

Data Source

PatentUS20240316258A1Systems, Apparatus and Methods for Processing Autologous Blood for Reinfusion into a Patient
Publication Date: 2024.09.26 RETRIEVER MEDICAL INC
  • US20240316258A1 patent drawing
  • US20240316258A1 patent drawing
  • US20240316258A1 patent drawing

AI summary

A blood reinfusion system for processing autologous blood for reinfusion into a patient. The system includes a blood reinfusion system having a blood processing canister with an internal fluid passageway. The internal fluid passageway includes a venturi region having a gravity-driven filtering system that is adapted to extract impurities from autologous blood without damaging the erythrocytes in the blood and, hence, inducing hemolysis of the erythrocytes in the blood, and loss of seminal native blood components, including native erythrocytes, platelets, white blood cells, plasma proteins and antibodies.