Green Tea Peptide Composition for Anti-Fatigue via Enzymatic Hydrolysis

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

In modern society, individuals often fail to achieve sufficient nutrition and rest to recover from physical fatigue due to busy lifestyles, necessitating the development of functional substances that can effectively suppress or recover from fatigue.

Innovation Solution

A composition comprising a green tea peptide with a novel amino acid sequence, isolated and purified through the culture of green tea protein and specific vegetable lactic acid bacteria, which inhibits fatigue substance production, increases ATP production, and promotes fat oxidation in muscle cells.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If green tea extract is used for anti-fatigue, then antioxidant effect is improved, but muscle cell penetration and anti-fatigue efficacy are insufficient

Engineering Contradiction:
Improveanti-fatigue efficacyVSAvoidmolecular structure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by breaking down green tea polyphenols (large molecules) into smaller peptide fragments through enzymatic hydrolysis. This segmentation transforms the large, complex polyphenol molecules into smaller peptide segments that can more effectively penetrate muscle cells while retaining antioxidant and anti-fatigue properties.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent extracts the active anti-fatigue components from green tea by isolating specific peptide sequences (SEQ ID NO: 1-7) through fermentation and purification processes. This extraction separates the beneficial peptide fragments from the complex green tea matrix, concentrating the anti-fatigue active ingredients.

Inventive Principle:
Principle #2Taking out (Extraction)

2Reliability

If conventional green tea polyphenols are used, then antioxidant power is improved, but muscle cell penetration ability deteriorates

Engineering Contradiction:
Improveantioxidant effectVSAvoidmolecule size
Core Design Contradiction:
ReliabilityVSLength of moving object

Solution Approach 1:

The patent segments large green tea polyphenol molecules into smaller peptide fragments through controlled enzymatic hydrolysis using vegetable lactic acid bacteria. This reduces molecular size from thousands of Daltons to hundreds of Daltons, enabling better muscle cell penetration while preserving antioxidant activity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the molecular parameters of green tea components by transforming polyphenols into peptides through fermentation. This parameter change (molecular weight, structure) improves penetration ability while maintaining or enhancing antioxidant efficacy.

Inventive Principle:
Principle #35Parameter changes

3Power

If high intensity exercise is performed, then energy expenditure is improved, but lactic acid accumulation increases causing fatigue

Engineering Contradiction:
Improveenergy expenditureVSAvoidlactic acid accumulation
Core Design Contradiction:
PowerVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful effect of lactic acid accumulation into a beneficial outcome by using green tea peptides to accelerate lactic acid metabolism and clearance. The peptides transform the fatigue-causing lactic acid buildup into an opportunity for enhanced recovery and performance.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent applies preliminary anti-action by pre-treating with green tea peptides before exercise to prevent excessive lactic acid accumulation. The peptides prepare the muscle cells to handle high-intensity exercise by enhancing their capacity to metabolize and clear lactic acid during and after exercise.

Inventive Principle:
Principle #9Preliminary anti-action

4Reliability

If sufficient nutrition and rest are provided, then fatigue recovery is improved, but time consumption increases

Engineering Contradiction:
Improvefatigue recoveryVSAvoidrecovery time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by providing green tea peptide supplementation before fatigue occurs or before exercise. This preparatory intake primes the body's anti-fatigue mechanisms, enabling faster recovery without requiring extended rest periods or additional nutrition intake.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent enables self-service recovery by using green tea peptides to activate the body's intrinsic fatigue recovery mechanisms. The peptides work with the body's natural processes to accelerate lactic acid clearance and energy replenishment, reducing dependence on external factors like extended rest or additional nutrition.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The green tea peptide composition effectively reduces fatigue by inhibiting lactic acid accumulation, enhancing ATP synthesis, and promoting mitochondrial biogenesis, thereby alleviating physical fatigue symptoms.

Implementation Method 1

a green tea peptide composition obtained by fermenting a green tea protein with vegetable lactic acid bacterium

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS20240189386A1Composition for Anti-fatigue comprising green tea peptide composition
Publication Date: 2024.06.13 AMOREPACIFIC CORP
  • US20240189386A1 patent drawing
  • US20240189386A1 patent drawing
  • US20240189386A1 patent drawing

AI summary

The present disclosure relates to a composition for anti-fatigue comprising a green tea peptide composition. Specifically, the green tea peptide composition according to the present disclosure exhibits anti-fatigue efficacy through excellent effects of inhibiting production of fatigue substances within a muscle cell, increasing ATP production within the muscle cell, and promoting fat oxidation within the muscle cell, and can be applied to various health functional food compositions and pharmaceutical compositions.