Green Tea Turmeric Extract Composition for Weight Loss

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Solution Overview

Problem

Current weight loss drugs have severe side effects and cardiovascular risks, limiting their safety and effectiveness for long-term use, particularly for patients with cardiovascular diseases, and fail to address the complex factors of obesity effectively.

Innovation Solution

A pharmaceutical composition comprising a specific ratio of green tea extract and turmeric extract, with optional resveratrol, which is administered to reduce body weight and body fat without affecting appetite or food intake, and is formulated into various dosage forms for oral or injectable administration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If current weight loss drugs are used to achieve weight loss effect, then weight loss is improved, but severe side effects and cardiovascular risks occur

Engineering Contradiction:

Improveweight loss effectVSAvoidside effects and cardiovascular risks

Core Design Contradiction:

ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces conventional synthetic weight loss drugs with plant-based extracts (green tea extract and turmeric extract) that have shorter action duration but safer profiles. These natural extracts achieve weight loss through gradual metabolic improvement rather than rapid suppression, reducing cardiovascular risks and severe side effects while maintaining effectiveness.

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent combines green tea extract (containing catechins) and turmeric extract (containing curcuminoids) in a composite formulation. This combination synergistically enhances weight loss effectiveness while the natural plant-based composition reduces harmful side effects and cardiovascular risks associated with conventional synthetic drugs.

Inventive Principle:

Principle #40Composite materials

2Productivity

If appetite suppression drugs are used to reduce food intake, then weight loss is improved, but cardiovascular risks increase

Engineering Contradiction:

Improveweight loss effectVSAvoidcardiovascular safety

Core Design Contradiction:

ProductivityVSReliability

Solution Approach 1:

The patent replaces the mechanical/chemical mechanism of appetite suppression (direct neural inhibition) with a metabolic mechanism (enhancing fat oxidation and energy expenditure). The plant extracts work by boosting metabolism and fat breakdown rather than suppressing hunger signals, thereby avoiding cardiovascular side effects while achieving weight loss.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If intestinal fat absorption blocking is used to reduce fat uptake, then weight loss is improved, but gastrointestinal side effects occur

Engineering Contradiction:

Improveweight loss effectVSAvoidgastrointestinal side effects

Core Design Contradiction:

ProductivityVSObject-generated harmful factors

Solution Approach 1:

Instead of blocking fat absorption in the intestine (preventing fat uptake), the patent takes the opposite approach by enhancing fat oxidation and metabolism after absorption. The plant extracts promote the breakdown and utilization of absorbed fats through metabolic pathways, avoiding gastrointestinal side effects while achieving weight loss through increased energy expenditure.

Inventive Principle:

Principle #13The other way round (Inversion)

Data Source

PatentUS10537605B2Composition of plant extract and its pharmaceutical composition and application thereof

Publication Date: 2020.01.21 CALIWAY BIOPHARM

AI summary

Provided is a plant extract composition and a pharmaceutical composition thereof for reducing body weight and body fat, wherein the plant extract composition comprises a green tea extract and a turmeric extract respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition. In diet-induced obesity models, either obesity is induced first or simultaneously with administration, the plant extract composition and a pharmaceutical composition thereof can reduce body weight and body fat more significantly than a single plant extract or commercially available weight loss drugs.