GUI for Automated Image Processing in High Content Screening

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Solution Overview

Problem

High content screening (HCS) and high throughput screening (HTS) systems require substantial user time and effort to manage and control automated image processing, data management, and analysis, leading to inefficiencies and potential errors.

Innovation Solution

A graphical user interface (GUI) is introduced to enable users to designate image naming conventions, sources, destinations, processing channels, parameter values, and spatial designations, facilitating the control of automated image processing and data analysis operations in HCS and HTS systems.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated image processing systems are used to quickly acquire and process large numbers of microscopic images, then productivity is improved, but device complexity increases and requires substantial user time and effort to manage and control

Engineering Contradiction:
Improveimage processing speedVSAvoidsystem operation complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

A graphical user interface (GUI) is introduced as an intermediary between the user and the complex automated image processing system. The GUI provides a standardized, user-friendly interface that abstracts the underlying system complexity, allowing users to control image acquisition, processing parameters, and data management without needing to understand the complex automated processes occurring behind the scenes.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system allows users to modify processing parameters through the GUI without changing the fundamental automated processing architecture. Users can adjust parameters such as image naming conventions, processing channels, and analysis settings, enabling flexible control over the image processing workflow while maintaining the automated high-speed processing capability.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If automated image processing systems process large numbers of images, then productivity is improved, but loss of time increases due to substantial user attention required for management and control

Engineering Contradiction:
Improveimage processing throughputVSAvoiduser time for system management
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The automated image processing system is designed to operate with minimal user intervention once configured. The system automatically acquires images, processes them according to predetermined parameters, and manages data output without requiring continuous user attention. The GUI enables users to set up processing workflows in advance, after which the system serves itself by autonomously completing the entire image processing pipeline.

Inventive Principle:
Principle #25Self-service

3Productivity

If automated image processing is implemented in HCS and HTS systems, then productivity is improved, but reliability decreases due to potential user errors in controlling operations

Engineering Contradiction:
Improvescreening throughputVSAvoidoperation accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The GUI acts as a protective intermediary that reduces the risk of user errors by providing a standardized interface with predefined options and parameters. Rather than allowing users to directly control complex automated processes where errors could occur, the GUI mediates user input through controlled selection options, reducing the likelihood of incorrect configurations or operational mistakes while maintaining high throughput capability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS8107711B2User interface method and system for management and control of automated image processing in high content screening or high throughput screening
Publication Date: 2012.01.31 VALA SCIENCES INC
  • US8107711B2 patent drawing
  • US8107711B2 patent drawing
  • US8107711B2 patent drawing

AI summary

A user interface method and system for controlling automated image processing operations of HCS and/or HTS systems includes a graphical interface to enable user designation of an image naming convention, image sources and destinations, image processing channels, processing parameter values, and processing spatial designations.