Guide Catheter Extension with Expandable Funnel for Wire Capture
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Solution Overview
Problem
The reverse CART procedure for chronic total occlusion in blood vessels faces challenges in capturing the retrograde wire within the shared subintimal space, leading to prolonged and complex procedures due to difficulty in locating the distal opening of the antegrade guide catheter.
Innovation Solution
A modified antegrade guide catheter extension system with a radially expandable distal opening, capable of forming a 'funnel-like' configuration, and an antegrade balloon catheter with a deformable shape memory scaffold structure to enhance wire capture and thrombus removal, facilitating efficient delivery and aspiration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of time
If a conventional guide catheter extension system is used, then the procedure can be performed, but the duration of the procedure is prolonged due to difficulty in locating and capturing the retrograde wire
Solution Approach 1:
The guide catheter extension system incorporates a radially expandable distal opening that can dynamically change its configuration. The opening transitions from a narrow state during insertion to an expanded funnel-like state for wire capture, allowing the device to adapt to different operational requirements and significantly improving wire capture ease while reducing procedure duration
Solution Approach 2:
The system pre-positions the guide catheter extension with a collapsible scaffold structure that is ready to expand. The balloon catheter is prepared to inflate and flare the scaffold before wire capture is needed, ensuring the distal opening is optimally configured in advance to receive and capture the retrograde wire, thereby reducing the time required for wire capture
2Ease of operation
If the distal opening is kept small for easy insertion, then insertion is simplified, but wire capture capability is reduced
Solution Approach 1:
The distal opening is designed with dynamic expandability, allowing it to remain small during insertion for ease of navigation into the subintimal space, then expand to a large funnel-like configuration when wire capture is required. This dynamic transformation resolves the contradiction between easy insertion and reliable wire capture
Solution Approach 2:
The guide catheter extension system applies different structural characteristics to different portions of the distal opening. The scaffold structure provides a collapsible framework that can be locally expanded at the distal end while maintaining a flexible proximal portion for easy insertion, creating localized functionality that satisfies both insertion ease and wire capture reliability
3Stability of the object's composition
If a rigid distal opening is used, then structural stability is maintained, but adaptability to different vessel configurations is reduced
Solution Approach 1:
The distal opening transitions from a rigid, narrow configuration during insertion to a flexible, expanded funnel-like structure for wire capture. The collapsible scaffold structure with balloon inflation enables dynamic adaptation to different subintimal space configurations while maintaining structural stability when needed, resolving the contradiction between stability and adaptability
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system significantly reduces the duration and complexity of the reverse CART procedure by improving wire capture and thrombus removal, enabling faster and more efficient interventions in chronic total occlusions.
Implementation Method 1
the balloon is inflated to flare the deformable shape memory scaffold structure to expand the distal opening
Implementation Method 2
a deformable shape memory scaffold structure, where the balloon is inflated to flare the deformable shape memory scaffold structure
Implementation Method 3
capable of deforming and expanding to form a 'funnel-like' distal opening at the distal end of the guide catheter extension system
Implementation Method 4
the flared scaffold structure can be plastically collapsed as it is withdrawn through the guide catheter
Implementation Method 5
The thrombus is removed by aspiration of the thrombus along the outer catheter lumen with the help of a vacuum system/syringe coupled to the proximal end of the outer thrombus removing catheter
Data Source
AI summary
The guide catheter extension system for various intravascular procedures, including the reverse CART procedure, the thrombus removal, etc., has an enhanced ”capturing” capability. It is configured with a plastically expandable scaffold member forming an expandable “funnel-like” distal opening, and, once it has been advanced into the subintimal space, provides an enhanced capability of catching the retrograde wire or a thrombus, as required by the procedure. A balloon delivered to the target location in the blood vessel, by being inflated, opens the scaffold member to enhance the delivery of the retrograde wire or the thrombus into the guide catheter extension. When the guide catheter extension is no longer needed, the flared guide extension can be easily compressed and collapsed as it is drawn in the guiding catheter. For benefits of the thrombus removal, the balloon may be formed from a material loaded with a radiopaque material and prefabricated with micro pores. A thrombolytic agent can be delivered to the thrombus before the thrombus is conveniently captured in the expanded distal opening of the scaffold member and removed from the blood vessel by aspiration. The outer or inner catheter may be configured with a distal curved portion to enhance a rotational capability for displacement between the right and left pulmonary arteries.