Handheld OCT Optical Layout for Self-Measured Retinal Thickness

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Solution Overview

Problem

Existing optical coherence tomography (OCT) systems for measuring retinal thickness are complex, expensive, and not suited for regular, in-home monitoring due to their size, weight, and requirement for trained operators, making them unsuitable for daily or weekly use and inaccessible to patients.

Innovation Solution

A compact, handheld OCT system with reduced optical path and weight, capable of measuring retinal thickness changes as small as 25 μm, designed for in-home use, featuring a light source that sweeps wavelengths from 3 nm to 10 nm, and circuitry that drives the light source with a sawtooth waveform for accurate and reliable measurements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If prior OCT systems are used for retinal thickness measurement, then measurement precision is achieved, but device complexity and cost increase significantly

Engineering Contradiction:
Improveretinal thickness measurement precisionVSAvoidOCT system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts only the essential OCT measurement functionality from complex clinical systems, implementing a simplified handheld device that performs retinal thickness measurement without requiring full clinical-grade system complexity. The invention isolates the core interferometric measurement capability while removing unnecessary auxiliary systems.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs cost-effective optical components and a simplified optical design that reduces system cost significantly compared to clinical OCT systems. The handheld device uses affordable light sources, detectors, and optical elements while maintaining sufficient measurement precision for retinal thickness monitoring.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Measurement precision

If prior OCT systems are used for retinal thickness measurement, then measurement precision is achieved, but weight and portability deteriorate

Engineering Contradiction:
Improveretinal thickness measurement precisionVSAvoidOCT system weight
Core Design Contradiction:
Measurement precisionVSWeight of moving object

Solution Approach 1:

The patent segments the OCT system into compact, integrated modules within a handheld form factor. The optical path is folded and miniaturized using discrete optical components arranged in a compact configuration, enabling the entire measurement system to fit in a portable device weighing only a fraction of clinical systems.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses folded optical paths and three-dimensional optical component arrangement to achieve compact physical dimensions while maintaining the required optical path length for OCT measurement. The optical bench is replaced with a compact optical train that achieves the same measurement capability in a handheld form factor.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Measurement precision

If prior OCT systems are used for retinal thickness measurement, then measurement precision is achieved, but ease of operation deteriorates due to trained operator requirement

Engineering Contradiction:
Improveretinal thickness measurement precisionVSAvoidoperator training requirement
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent implements automated alignment and measurement acquisition features that eliminate the need for trained operators. The handheld device includes automatic eye tracking, automated focus acquisition, and software-guided measurement protocols that enable patients or caregivers to perform measurements without specialized training while maintaining measurement precision.

Inventive Principle:
Principle #25Self-service

4Productivity

If in-home monitoring is implemented, then productivity and accessibility improve, but reliability may deteriorate due to handling hazards

Engineering Contradiction:
Improvemonitoring frequencyVSAvoidmeasurement reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent designs the handheld OCT device with robust mechanical structures that can withstand drops and handling hazards. The optical components are mounted on vibration-isolated platforms, and the device includes protective casing and shock-absorbing elements that maintain measurement reliability even after accidental drops during home use.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compact OCT system allows for accurate and reliable in-home monitoring of retinal thickness, providing repeatability and reproducibility within acceptable tolerances, enabling patients to measure themselves and reducing healthcare costs by eliminating the need for frequent clinical visits.

Implementation Method 1

a light source that sweeps wavelengths from 3 nm to 10 nm

Methodology Applied
Scientific EffectWavelength sweeping:

Implementation Method 2

optical coherence tomography (OCT) system

Methodology Applied
Scientific EffectOptical interference: Interference

Data Source

PatentUS11890053B2Miniaturized mobile, low cost optical coherence tomography system for home based ophthalmic applications
Publication Date: 2024.02.06 ACUCELA INC
  • US11890053B2 patent drawing
  • US11890053B2 patent drawing
  • US11890053B2 patent drawing

AI summary

Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.