Handheld OCT Retinal Thickness Measurement

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Solution Overview

Problem

Existing optical coherence tomography (OCT) systems are complex, expensive, and not suited for regular, in-home monitoring of retinal thickness, requiring trained operators and being cumbersome for daily use, which limits their accessibility and effectiveness in managing retinal diseases.

Innovation Solution

A compact, handheld OCT system with improved signal processing capabilities that allows patients to measure retinal thickness accurately, featuring a processor-driven interferometer with enhanced scanning patterns and alignment techniques to improve resolution of retinal structures, enabling in-home and mobile monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If prior OCT systems are used for retinal thickness measurement, then measurement capability is provided, but device complexity and cost increase, making them unsuitable for regular in-home monitoring

Engineering Contradiction:
Improveretinal thickness measurementVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential OCT measurement functionality from complex clinical systems, isolating the core interferometer and signal processing components needed for retinal thickness measurement while removing unnecessary complexity. This enables a simplified handheld device that maintains measurement capability for monitoring retinal diseases.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a simplified copy of clinical OCT systems by implementing the core optical coherence tomography principle using a compact interferometer and basic optical components. This copy provides sufficient measurement precision for in-home monitoring without replicating the full complexity of clinical systems.

Inventive Principle:
Principle #26Copying

2Measurement precision

If prior OCT systems are used for retinal monitoring, then retinal thickness can be measured, but the systems are expensive and not affordable for typical patients

Engineering Contradiction:
Improveretinal thickness measurementVSAvoidsystem cost
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent adopts a cost-reduction strategy by using affordable optical components and simplified manufacturing approaches. The handheld OCT system uses standard optical elements and integrated circuits that can be manufactured at lower cost, making the device accessible to typical patients for regular monitoring.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Measurement precision

If prior OCT systems are used, then retinal measurement is possible, but they require trained operators and are not suitable for patient self-monitoring

Engineering Contradiction:
Improveretinal thickness measurementVSAvoidoperator training requirement
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent implements automatic alignment and measurement features that eliminate the need for trained operators. The system includes automated eye tracking, focus adjustment, and retinal layer identification algorithms that guide the patient through the measurement process independently, enabling self-monitoring at home.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent incorporates real-time feedback mechanisms including visual guidance displays, automated quality assessment of retinal images, and instructional prompts that help patients perform measurements correctly without operator intervention. The system provides immediate feedback on measurement quality and guides users through the process.

Inventive Principle:
Principle #23Feedback

4Measurement precision

If prior OCT systems are used, then retinal thickness can be measured, but the systems are cumbersome and not suitable for travel or mobile use

Engineering Contradiction:
Improveretinal thickness measurementVSAvoidsystem portability
Core Design Contradiction:
Measurement precisionVSWeight of moving object

Solution Approach 1:

The patent implements a compact handheld design where optical components, electronics, and power supply are nested within a portable housing. The interferometer, scanners, and detectors are integrated into a space-efficient configuration that fits in a handheld form factor, enabling easy transport and mobile use while maintaining measurement precision.

Inventive Principle:
Principle #7Nested doll (Nesting)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides precise and accessible retinal thickness measurements, allowing for timely adjustments in treatment and improved patient care by enabling regular monitoring and data analysis for healthcare providers.

Implementation Method 1

a light source to generate a measurement beam

Methodology Applied
Scientific EffectCoherent light generation: Coherent Light

Implementation Method 2

an interferometer with an OCT measurement beam

Methodology Applied
Scientific EffectOptical interference: Interference

Data Source

PatentUS11974807B2System and method for optical coherence tomography a-scan decurving
Publication Date: 2024.05.07 ACUCELA INC
  • US11974807B2 patent drawing
  • US11974807B2 patent drawing
  • US11974807B2 patent drawing

AI summary

An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. Measurement data may be processed using a decurving process to enhance the resolution of the ILM layer and provide improved determinations of retinal thickness.