Handheld Optical Probe with 3D Tracking for Breast Imaging

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Solution Overview

Problem

Existing NIR optical imaging systems for breast cancer diagnostics are limited by their bulkiness, inability to conform to different tissue curvatures, and slow data capture rates due to single point illumination and detection geometries, leading to increased patient discomfort and limited 3-D tomography capabilities.

Innovation Solution

A flexible optical imaging system with simultaneous multiple point illumination and detection, combined with tracking facilities for co-registering location data, enabling the generation of 3-D tomographic data by using a probe head with pivotable sections and ultrasonic tracking for precise positioning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional NIR optical imaging systems are used, then imaging capability is provided, but the systems are large and bulky, reducing portability

Engineering Contradiction:
ImproveportabilityVSAvoidsystem size
Core Design Contradiction:
Adaptability or versatilityVSVolume of moving object

Solution Approach 1:

The imaging system is divided into separate functional modules: a hand-held probe unit for data acquisition, a tracking system for position monitoring, and a separate processing unit for image reconstruction. This segmentation allows the imaging functionality to be portably deployed while maintaining system capabilities.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A tracking system acts as an intermediary between the hand-held probe and the imaging processing system, enabling the probe to be freely positioned while maintaining accurate spatial registration for 3-D tomographic reconstruction.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If conventional NIR optical imaging systems are used, then imaging is performed, but the apparatus requires patient positioning or tissue compression, increasing patient discomfort

Engineering Contradiction:
Improvepatient comfortVSAvoidpatient discomfort
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The system transitions from static imaging requiring fixed patient positioning to dynamic handheld probing that can adapt to various patient positions and anatomical configurations, reducing discomfort while maintaining imaging quality.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The measurement geometry changes from fixed to variable, allowing the probe to be positioned at multiple locations and angles without requiring tissue compression or restrictive patient positioning, thereby improving comfort.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If conventional NIR optical imaging systems are used, then imaging is performed, but only fixed volumes or certain shapes of breast tissue can be imaged

Engineering Contradiction:
Improveimaging volume flexibilityVSAvoidimaging geometry constraint
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The hand-held probe combined with 3-D tracking enables the system to image various tissue volumes and shapes by moving the probe to different positions, providing universal applicability across different anatomical configurations rather than being limited to fixed geometries.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Productivity

If single point illumination and detection measurement geometries are used, then simplified measurement is achieved, but data acquisition rates are limited, increasing patient wait time

Engineering Contradiction:
Improvedata acquisition rateVSAvoidpatient wait time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The system adds the temporal dimension by acquiring data at multiple probe positions simultaneously through multi-point detection, transforming single-point sequential measurement into multi-point parallel measurement, thereby dramatically increasing data acquisition rate.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

5Adaptability or versatility

If hand-held optical imagers with flat measuring probe heads are used, then portability is improved, but the probe cannot conform to different tissue curvatures

Engineering Contradiction:
Improvetissue curvature conformanceVSAvoidprobe head geometry
Core Design Contradiction:
Adaptability or versatilityVSShape

Solution Approach 1:

The probe head transitions from a static flat geometry to a dynamic configuration that can adapt to tissue curvatures through flexible positioning and multiple measurement points, enabling conformance to various anatomical surfaces.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for more comfortable and efficient 3-D imaging of breast tissue, reducing patient discomfort and enhancing data acquisition rates, thereby improving the accuracy and speed of breast cancer diagnostics.

Implementation Method 1

Near-infrared (NIR) optical imaging is an emerging non-invasive technology that may be applied towards deep tissue imaging

Methodology Applied
Scientific EffectNear-infrared optical imaging: Absorption (EM radiation)

Implementation Method 2

ultrasonic tracking for precise positioning

Methodology Applied
Scientific EffectUltrasonic tracking: Ultrasound

Data Source

PatentUS8712504B2Hand-held optical probe based imaging system with 3D tracking facilities
Publication Date: 2014.04.29 FLORIDA INTERNATIONAL UNIVERSITY
  • US8712504B2 patent drawing
  • US8712504B2 patent drawing
  • US8712504B2 patent drawing

AI summary

A method, apparatus, and system display image data for a three-dimensional object in real-time, co-registering the image data acquired from a probe with the location on the three-dimensional object from which the image data was acquired, by tracking the position and orientation of the probe as the probe acquires the image data.