High Boiling Point Solvent Cadaverine Purification
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Solution Overview
Problem
Current methods for purifying bio-based cadaverine from cadaverine salt compositions are inefficient due to involatile impurities, requiring high heating temperatures and long evaporation/distillation times, resulting in low recovery yields and potential contamination.
Innovation Solution
The method involves adding high boiling point solvents to the evaporation/distillation system to improve fluidity, allowing for lower heating temperatures and shorter times while recovering the solvents to maintain efficiency and reduce costs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If evaporation/distillation is performed without adding solvents, then the process is simple, but high heating temperature and long time are required resulting in low recovery yield
Solution Approach 1:
A high boiling point solvent is introduced as an intermediary substance to facilitate the separation of cadaverine from involatile impurities. The solvent selectively interacts with cadaverine, enabling its extraction and concentration without requiring extreme heating conditions, thus resolving the contradiction between recovery yield and heating temperature.
Solution Approach 2:
The invention changes the physical-chemical parameters of the system by introducing a solvent that alters the volatility characteristics and solubility relationships. This allows cadaverine to be separated at lower temperatures through solvent-mediated phase separation rather than direct thermal evaporation, improving recovery yield while reducing heating requirements.
2Productivity
If evaporation/distillation is performed without adding solvents, then no solvent recovery is needed, but long evaporation/distillation time is required
Solution Approach 1:
The high boiling point solvent acts as a mediator that accelerates the purification process by selectively dissolving cadaverine and separating it from impurities through liquid-liquid extraction. This solvent-mediated separation is much faster than direct evaporation, improving purification speed while reducing the time required despite the need for subsequent solvent recovery.
3Productivity
If high heating temperature is used for evaporation/distillation, then evaporation rate is high, but cadaverine quality deteriorates due to contamination and decomposition
Solution Approach 1:
The solvent serves as a protective intermediary that enables cadaverine separation through selective solubility rather than thermal volatility. This allows high-purity cadaverine recovery at lower temperatures, preventing thermal decomposition and contamination while maintaining efficient separation rates through solvent-cadaverine interactions.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach significantly increases cadaverine recovery yield and quality by reducing heating temperatures and times, minimizing contamination, and enabling the recycling of solvents, thus enhancing industrial applicability and environmental sustainability.
Implementation Method 1
evaporation/distillation of cadaverine from an aqueous cadaverine composition
Implementation Method 2
distilling or evaporating the aqueous cadaverine composition wherein one or more solvents are added to the evaporation/distillation system
Data Source
AI summary
One aspect of the invention relates to a method for the purification of cadaverine from an aqueous cadaverine composition comprising one or more involatile impurities, the method comprising: a) distilling or evaporating the aqueous cadaverine composition wherein one or more solvents are added to the evaporation/distillation system before the evaporation/distillation starts, during the evaporation/distillation and/or after the evaporation/distillation substantially stops when no more evaporation/distillation is observed to produce purified cadaverine, wherein the evaporation or distillation is done at a heating temperature of about 80° C. to about 180° C. and under a pressure of 1 atm or lower, and the one or more solvents comprise at least one or more high boiling point (HBP) solvents having a boiling point of at least about 185° C. (1 atm); and b) recovering the one or more HBP solvents.