3D Heart Blood Flow Reporting for Noninvasive Coronary Function
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Solution Overview
Problem
Current diagnostic methods for coronary artery disease, such as CCTA and CCA, fail to provide accurate, noninvasive assessment of coronary lesions' functional significance, leading to unnecessary invasive procedures and increased healthcare costs.
Innovation Solution
A system and method for creating a patient-specific three-dimensional model of the heart using noninvasive data, solving equations to determine blood flow characteristics like cFFR, and generating reports to guide treatment decisions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional coronary angiography (CCA) is used to visualize coronary lesions, then anatomic data on lesion size and shape is obtained, but functional significance of the lesions cannot be assessed
Solution Approach 1:
The patent combines conventional coronary angiography (CCA) with fractional flow reserve (FFR) measurement in a single integrated diagnostic process. The system merges anatomic imaging data with functional hemodynamic data by simultaneously acquiring coronary artery images and pressure measurements, then processing them together to assess both the structural and functional characteristics of coronary lesions.
Solution Approach 2:
The diagnostic system performs multiple functions in one procedure: it visualizes coronary anatomy, measures pressure gradients across lesions, calculates FFR values, and provides comprehensive assessment of both anatomic and functional lesion characteristics. This multi-functional approach eliminates the need for separate diagnostic procedures.
2Measurement precision
If invasive FFR measurement is performed to assess functional significance, then accurate blood flow data is obtained, but patient risk and procedure complexity increase
Solution Approach 1:
The system performs FFR assessment during the routine diagnostic catheterization procedure before any therapeutic interventions are planned or executed. By obtaining functional data during the initial diagnostic procedure, the system eliminates the need for additional invasive procedures that would expose patients to further risks.
Solution Approach 2:
The system utilizes the existing catheter access and imaging infrastructure already in place during coronary angiography to perform FFR measurements. The diagnostic procedure serves dual purposes: visualizing anatomy and assessing function, thereby eliminating the need for separate invasive testing.
3Loss of information
If separate diagnostic procedures are performed for anatomy and function, then comprehensive data is collected, but healthcare costs and patient burden increase
Solution Approach 1:
The patent integrates multiple diagnostic modalities into a single unified procedure. Conventional coronary angiography and FFR measurement are combined, allowing simultaneous acquisition of anatomic and functional data without requiring separate procedural sessions.
Solution Approach 2:
The diagnostic system is designed to perform multiple assessment functions within one procedure, including coronary imaging, pressure measurement, flow assessment, and comprehensive lesion characterization, thereby reducing the total number of procedures required.
Data Source
AI summary
Embodiments include a system for displays cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The computer system may determine at least one value of the blood flow characteristic within the patient's heart based on the model. The computer system may also display a report comprising a representation of at least one artery corresponding to at least a portion the model, and display one or more indicators of the value of the blood flow characteristic on a corresponding portion of the at least one artery.


