Heart Tissue Risk Visualization Using Non-Invasive Phase Space Analysis
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Solution Overview
Problem
Current methods for visualizing coronary artery blockages and myocardium at risk are invasive, costly, and carry risks such as stroke and radiation exposure, while also being time-consuming and requiring expertise for interpretation.
Innovation Solution
The development of a non-invasive system that uses phase space tomography analysis to present data in a graphical user interface, allowing for three-dimensional and two-dimensional visualizations of myocardial tissue, coronary arteries, and predicted CAD status, facilitating intuitive and unified visualization for diagnosis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If invasive procedures such as coronary angiography are used to measure occlusion size and blood flow, then measurement precision is improved, but object-affected harmful factors increase due to risks of stroke, heart attack, radiation exposure, and injury
Solution Approach 1:
The patent replaces the mechanical/invasive catheter-based measurement system with a non-invasive electrical measurement system that uses body surface potential maps to assess coronary artery disease, thereby eliminating the harmful effects of invasive procedures while maintaining diagnostic capability
Solution Approach 2:
The patent introduces an intermediary computational model that translates non-invasive electrical measurements into meaningful diagnostic information about coronary artery blockages, allowing accurate assessment without direct physical intrusion into the vascular system
2Measurement precision
If invasive catheterization procedures are performed to evaluate coronary arteries, then measurement precision is improved, but loss of time increases due to the lengthy and complex nature of the procedure
Solution Approach 1:
The patent substitutes the time-consuming mechanical catheterization process with a rapid non-invasive electrical measurement approach that can be performed quickly without the need for complex procedural setup and interpretation
3Object-affected harmful factors
If contemporary techniques using surface cardiac gradient analysis are used, then object-generated harmful factors are reduced by avoiding invasive procedures, but difficulty of detecting and measuring increases due to noise contamination and challenge in discriminating pertinent information
Solution Approach 1:
The patent introduces an intermediary computational processing layer that filters and interprets the noisy electrical signals from the body surface, extracting meaningful diagnostic information about coronary artery disease while eliminating the need for invasive measurement
Solution Approach 2:
The patent creates a computational model that replicates the diagnostic information obtainable from invasive procedures by analyzing patterns in non-invasive electrical measurements, effectively copying the diagnostic value without the harmful effects
Data Source
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AI summary
Exemplified methods and systems facilitate presentation of data derived from measurements of the heart in a non-invasive procedure (e.g., via phase space tomography analysis). In particular, the exemplified methods and systems facilitate presentation of such measurements in a graphical user interface, or "GUI" (e.g., associated with a healthcare provider web portal to be used by physicians, researchers, or patients, and etc.) and/or in a report for diagnosis of heart pathologies and disease. The presentation facilitates a unified and intuitive visualization that includes three-dimensional visualizations and two-dimensional visualizations that are concurrently presented within a single interactive interface and/or report.