Heart Rotor Detection Using Electrogram Analysis
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Solution Overview
Problem
Current methods for treating cardiac fibrillation are costly and invasive, making it difficult to effectively target and treat the underlying heart rotors that cause turbulent cardiac electrical activity.
Innovation Solution
A method involving multiple electrodes to record and analyze electrograms, calculating time amplitude integral scores, and identifying sites with high scores or intrinsic deflections greater than 40 msec to locate likely heart rotor sites, followed by targeted ablation to treat cardiac fibrillation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If multiple high fidelity microelectrodes are inserted inside cardiac muscle cells to record electric signals, then measurement precision is improved, but device complexity and ease of operation deteriorate
Solution Approach 1:
The patent uses an intermediary approach by employing a catheter with multiple electrodes that can be positioned in the heart chamber without inserting electrodes directly into cardiac muscle cells. This mediator (catheter system) enables electrical signal recording with sufficient precision while dramatically reducing the complexity and invasiveness compared to direct intracellular electrode insertion
Solution Approach 2:
The patent replaces the complex mechanical system of intracellular electrode insertion with a less invasive extracellular recording system. Instead of mechanically inserting multiple high fidelity microelectrodes into individual cardiac muscle cells, the system uses a catheter-based approach that records electrical signals from the heart chamber, maintaining measurement precision while reducing operational difficulty
2Reliability
If traditional cardiac fibrillation treatment methods are used, then treatment effectiveness is achieved, but loss of time and loss of substance increase
Solution Approach 1:
The patent applies preliminary action by first identifying and localizing the specific rotor sites responsible for fibrillation through electrogram analysis before performing ablation. This preliminary localization enables targeted treatment rather than extensive exploratory procedures, reducing the time and resources required for successful fibrillation treatment
Solution Approach 2:
The patent implements local quality by focusing the ablation treatment specifically at the identified rotor sites rather than applying treatment broadly across the heart. This localized approach maintains treatment effectiveness while significantly reducing the total time and substance (energy, materials) consumed during the procedure
3Measurement precision
If extensive cardiac mapping and analysis is performed to identify rotor sites, then measurement precision is improved, but loss of time increases
Solution Approach 1:
The patent applies parameter changes by transforming the electrogram data into derived parameters such as time-amplitude integral scores and intrinsic deflection measurements. These parameter transformations enable automated comparison and identification of rotor sites, improving measurement precision while reducing manual analysis time through objective quantitative criteria
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables minimally invasive treatment of cardiac fibrillation by accurately identifying and treating heart rotor sites, reducing recovery times, patient discomfort, and treatment costs.
Implementation Method 1
In the heart muscle cell, electric activation occurs from the inflow of sodium ions across the cell membrane. The maximum amplitude of the action potential is about 100 mV.
Data Source
AI summary
This document provides devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for detecting heart rotors such that effectively targeted cardiac fibrillation treatments can be provided.