Heat Block Assembly for Organic Synthesis Temperature Control

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Solution Overview

Problem

Conventional organic compound synthesizing methods using combinatorial chemistry face inefficiencies in synthesizing organic compounds, particularly in maintaining optimal temperature conditions for reaction containers, which affects the yield and purity of synthesized compounds.

Innovation Solution

A heat block assembly with temperature-adjustable grooves for reaction containers, allowing for precise temperature control between upper and lower heat blocks, enhancing the thermal management and reaction efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional block assembly without temperature control is used, then device complexity is reduced, but synthesizing efficiency and compound yield are insufficient

Engineering Contradiction:
Improvesynthesizing efficiencyVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent introduces temperature as a controllable parameter by integrating heat blocks with temperature adjustors into the block assembly. This allows precise temperature control during organic compound synthesis reactions, thereby improving synthesizing efficiency and compound yield without significantly complicating the overall device structure.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The heat blocks serve as intermediary components between the temperature adjustor and the reaction containers. These heat blocks transfer controlled thermal energy to the reaction vessels, enabling precise temperature management for chemical reactions while maintaining a clear functional separation that minimizes device complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Manufacturing precision

If temperature control is added to improve reaction conditions, then compound yield and purity increase, but device complexity increases

Engineering Contradiction:
Improvecompound purityVSAvoiddevice complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

By incorporating temperature adjustors and heat blocks, the system gains precise control over reaction temperature parameters. This enables optimization of reaction conditions to improve compound purity and yield, with the temperature control mechanism integrated directly into the existing block assembly structure to minimize additional complexity.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If multiple heat blocks are used for precise temperature control, then synthesizing efficiency improves, but device complexity and cost increase

Engineering Contradiction:
Improvesynthesizing efficiencyVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system divides the heating function into multiple independent heat blocks, each capable of being inserted into or removed from the block assembly. This segmentation allows flexible configuration where heat blocks are added only when and where needed for specific reactions, improving synthesizing efficiency while avoiding unnecessary complexity in situations where simpler heating suffices.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The improved temperature control significantly increases the yield and purity of synthesized compounds by maintaining optimal conditions during the synthesis process, thereby enhancing the overall synthesizing efficiency.

Implementation Method 1

a temperature adjustor for adjusting the temperature of the heat block

Methodology Applied
Scientific EffectTemperature control: Heating

Implementation Method 2

one or more heat blocks provided with grooves in which reaction containers are inserted

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS7687043B2Heat block assembly and organic compound synthesizing apparatus using the heat block assembly
Publication Date: 2010.03.30 PEPTRON
  • US7687043B2 patent drawing
  • US7687043B2 patent drawing
  • US7687043B2 patent drawing

AI summary

A heat block assembly and an organic compound synthesizing apparatus using the heat block assembly are provided. The heat block assembly includes one or more heat blocks provided with grooves in which reaction containers are inserted, and a temperature adjustor for adjusting the temperature of the heat block.