Devices for control of condensation and methods of use thereof

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Solution Overview

Problem

Existing thermal incubation devices often create unwanted temperature gradients, leading to condensation at the top of sample containers, which reduces sample volume and can alter assay results, and existing solutions like heated covers or mineral oil are not effective or compatible with automated processes.

Innovation Solution

A heating element with an opening above the sample well, positioned to heat the top surface of the container, maintaining the top surface at a temperature higher than the sample well, thereby preventing condensation, and allowing for automated access and processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If a heated cover is used to prevent condensation, then condensation is minimized, but access to the sample becomes difficult

Engineering Contradiction:
ImprovecondensationVSAvoidaccess to sample
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The heating element is segmented into a frame structure with four sides and an open top, allowing the heating function to be separated from the sample access path. This enables samples to be accessed through the open top while the sides remain heated to prevent condensation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The cover is completely removed from the heating element design, extracting the obstruction that prevented sample access. The heating function is maintained through the side walls and base, while the top remains open for easy sample manipulation.

Inventive Principle:
Principle #2Taking out (Extraction)

2Object-affected harmful factors

If mineral oil is used to create a vapor barrier, then condensation is prevented, but sample access becomes cumbersome and assay compatibility is limited

Engineering Contradiction:
ImprovecondensationVSAvoidassay compatibility
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

A frame-shaped heating element acts as an intermediary structure that provides thermal control without requiring chemical additives. The heating element mediates between the heat source and the sample, preventing condensation through thermal management rather than chemical barriers.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Device complexity

If the top of the container is not heated, then the heating element structure is simple, but temperature gradients cause condensation

Engineering Contradiction:
Improveheating element structureVSAvoidcondensation
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The heating element applies heat locally to the sides and base of the container through its frame structure, creating a temperature gradient that prevents condensation on the container walls while leaving the top open for access. This localized heating approach targets the specific areas where condensation forms.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively minimizes condensation, maintains sample volume, and enables efficient automated processing by maintaining the top surface of the container at a higher temperature than the sample well, preventing condensation and allowing for direct access and manipulation of samples.

Implementation Method 1

a heating element positioned above a frame having at least one well for holding a liquid sample, where the heating element includes an opening above the well and is positioned to heat the opening

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS10330343B2Devices for control of condensation and methods of use thereof
Publication Date: 2019.06.25 T2 BIOSYSTEMS INC
  • US10330343B2 patent drawing
  • US10330343B2 patent drawing

AI summary

The present invention relates to devices including a heating element with an opening, which can control condensation of liquid samples during thermal incubation. The opening of the heating element can provide direct access to the samples in a process that may be automated. The invention also provides methods for heating containers.