Heatmap-Guided Feature Selection for Hyperspectral Retinal Imaging

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Solution Overview

Problem

Hyperspectral and multispectral fundus imaging generates vast amounts of data, making it challenging to analyze effectively for diagnostic purposes, particularly in automated methods like machine learning, due to the complexity of processing spatial and spectral data for retinal image analysis.

Innovation Solution

A method involving heatmap-based feature preselection is employed, which includes generating heatmaps to emphasize significant and predictive data for disease detection by leveraging both spatial and spectral information, using pixel-wise statistical tests to identify relevant spatial anatomical regions and calculating discriminative power, thereby automating feature selection for machine learning models.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If hyperspectral and multispectral fundus imaging is used to capture detailed retinal data, then diagnostic information quality is improved, but data processing complexity increases

Engineering Contradiction:
Improvediagnostic information qualityVSAvoiddata processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts only the most informative spectral bands and spatial regions from the vast hyperspectral data. By using heatmaps to identify and select top-k discriminative features, the system extracts essential diagnostic information while discarding redundant data, thus reducing processing complexity while maintaining diagnostic quality.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent segments the retinal image into multiple spectral bands and spatial regions, then systematically evaluates each segment's contribution to disease detection. This segmentation allows the system to process data in manageable portions and identify which segments are most diagnostically relevant, reducing overall processing complexity.

Inventive Principle:
Principle #1Segmentation

2Productivity

If automated machine learning methods are applied to retinal image analysis, then diagnostic efficiency is improved, but feature selection difficulty increases

Engineering Contradiction:
Improvediagnostic efficiencyVSAvoidfeature selection difficulty
Core Design Contradiction:
ProductivityVSDifficulty of detecting and measuring

Solution Approach 1:

The patent implements a self-service feature selection mechanism where the system automatically evaluates spectral bands and spatial regions against the diagnostic task requirements. The heatmap-based approach enables the system to self-determine which features are most discriminative without human intervention, streamlining the feature selection process for machine learning models.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent uses feedback from discriminative power calculations and statistical tests to iteratively refine feature selection. By continuously evaluating which spectral bands and spatial regions provide the most diagnostic information, the system adjusts its feature selection dynamically, making the complex feature selection process more manageable and automated.

Inventive Principle:
Principle #23Feedback

3Reliability

If the entire retinal image dataset is processed for analysis, then comprehensive diagnostic coverage is improved, but computational resource consumption increases

Engineering Contradiction:
Improvediagnostic coverageVSAvoidcomputational resource consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The patent extracts only the top-k most discriminative spectral bands and spatial regions identified through heatmap analysis. By focusing computational resources only on these selected features rather than processing the entire dataset, the system maintains comprehensive diagnostic coverage for the most relevant pathological features while significantly reducing computational energy consumption.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS20250336062A1Heatmap based feature preselection for retinal image analysis
Publication Date: 2025.10.30 OPTINA DIAGNOSTICS
  • US20250336062A1 patent drawing
  • US20250336062A1 patent drawing
  • US20250336062A1 patent drawing

AI summary

Systems and methods described herein process retinal image data and select features that are most useful in the detection of disease. The systems/methods generate heatmaps indicating the discriminative power of various spatial/spectral information and use the heatmaps for feature selection and training of ML models.