Hematocrit Measurement Using Multi-Angle Light Scattering
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The measurement precision of fluids is reduced due to changes in fluid components affecting the relationship among scatter components, particularly when using side scattered light, which is not effectively harnessed in existing methods.
Innovation Solution
A measuring apparatus and method that utilize three light receivers to detect forward, backscatter, and side scatter components of light scattered by a fluid, allowing for accurate fluid information output by using the sum of backscatter and side scatter components in conjunction with forward scatter components.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If side scattered light is used for measurement, then measurement information can be obtained, but measurement precision is reduced due to changes in fluid components affecting the relationship among scatter components
Solution Approach 1:
The scattered light is segmented into three distinct components: forward scattered light, backscattered light, and side scattered light. Each component is detected by a separate light receiver, allowing independent measurement of each scatter component. This segmentation enables the system to capture comprehensive scattering information while maintaining measurement precision despite fluid component variations.
Solution Approach 2:
The measurement system transitions from detecting only forward and backscattered light to including side scattered light detection. By adding the side scatter component detection at a substantially perpendicular angle to the optical axis, the system expands the measurement dimensionality, capturing more comprehensive fluid information that remains stable across different fluid compositions.
2Measurement precision
If multiple scatter components are detected, then fluid information can be measured, but device complexity increases
Solution Approach 1:
The measuring device is designed with multi-functionality by incorporating three light receivers that can detect different scatter components simultaneously. Each receiver serves a specific detection function, but collectively they provide comprehensive fluid characterization. This universal design allows the same device structure to handle various fluid types and compositions without requiring additional specialized components.
Solution Approach 2:
The system merges the detection of forward, backscatter, and side scatter components into a single integrated measurement process. By combining the signals from all three light receivers, the system achieves comprehensive fluid information measurement. The control unit processes all three signals together to determine fluid properties, eliminating the need for separate measurement systems for each scatter component.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables more precise fluid information measurement, such as hematocrit values, by establishing a fixed relation between the sum of backscatter and side scatter components and forward scatter components, improving measurement accuracy compared to using only one or two scatter components.
Implementation Method 1
irradiation light is scattered in a plurality of directions
Implementation Method 2
a first light receiver configured to receive a forward scatter component of scattered light; a second light receiver configured to receive a backscatter component of the scattered light; a third light receiver configured to receive a side scatter component of the scattered light
Data Source
Figure 1
Figure 2
Figure 3
AI summary
A measuring apparatus is provided with: an irradiator configured to irradiate fluid with light; a first light receiver configured to receive a forward scatter component of scattered light scattered by the fluid; a second light receiver configured to receive a backscatter component of the scattered light; a third light receiver configured to receive a side scatter component of the scattered light; and an outputting device configured to output fluid information about the fluid, which is obtained on the basis of light receiving signals of the first light receiver, the second light receiver, and the third light receiver. According to this measuring apparatus, it is possible to output accurate fluid information because of the use of the forward scatter component, the backscatter component, and the side scatter component of the scattered light.