Automated Hematoma Detection in Non-Contrasted CT Images

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Solution Overview

Problem

Current methods for diagnosing hemorrhagic stroke in CT images are inadequate, particularly for non-contrasted images, and often require expert specialists, leading to delayed or inappropriate treatment due to the lack of effective differential diagnosis tools.

Innovation Solution

A system that extracts candidate regions suspected of being acute hematomas from non-contrasted CT images using gray value analysis and classifies them based on spatial features such as size, shape, and connectedness to the skull, allowing for accurate differentiation between true and false hematomas without the need for contrast agents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If expert specialists perform manual diagnosis of stroke in CT images, then diagnostic accuracy is improved, but treatment time is delayed and accessibility is reduced

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidtreatment time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system enables automated self-diagnosis of stroke types by analyzing CT images through gray value characteristics and spatial features, allowing the computer system to perform the diagnostic function independently without requiring expert specialist intervention, thus resolving the contradiction between maintaining high diagnostic accuracy and reducing treatment time delays

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the manual mechanical diagnostic process performed by experts with an automated computer-based image analysis system that uses algorithmic processing of gray value distributions and spatial relationships in CT images, substituting human expertise with automated computational methods to achieve both accuracy and speed

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Loss of time

If automated image processing methods are used for stroke detection, then treatment time is reduced, but diagnostic accuracy deteriorates due to inability to differentiate true hematomas from artifacts

Engineering Contradiction:
Improvetreatment timeVSAvoiddiagnostic accuracy
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The system applies different analytical approaches to different regions of the CT image: gray value analysis for identifying candidate regions, and spatial feature analysis for validating true hematomas. This localized application of different processing qualities enables automated speed while maintaining diagnostic accuracy through region-specific validation

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent combines multiple analysis methods (gray value thresholding, clustering, and spatial feature validation) into a composite diagnostic approach, where each method compensates for the weaknesses of others, achieving both automated processing speed and high diagnostic accuracy by integrating diverse analytical techniques

Inventive Principle:
Principle #40Composite materials

3Productivity

If rule-based approaches with symmetry assumptions are applied, then processing speed is improved, but diagnostic accuracy worsens for acute haemorrhagic stroke detection

Engineering Contradiction:
Improveprocessing speedVSAvoiddiagnostic accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system changes the diagnostic parameters from symmetry-based features to gray value distribution and spatial relationship features that are specific to acute haemorrhagic stroke. This parameter transformation maintains processing speed while improving accuracy by using parameters that actually differentiate hemorrhagic from ischemic stroke

Inventive Principle:
Principle #35Parameter changes

4Difficulty of detecting and measuring

If thresholding and clustering methods are used for acute haemorrhage detection, then detection capability is improved, but false positive rate increases due to skull-brain interface artifacts

Engineering Contradiction:
Improvedetection capabilityVSAvoidfalse positive rate
Core Design Contradiction:
Difficulty of detecting and measuringVSReliability

Solution Approach 1:

The system extracts and separately analyzes spatial features of candidate regions identified by thresholding and clustering. By extracting the candidate regions and applying additional spatial validation, the system separates true hematoma detection from artifact identification, maintaining high detection capability while reducing false positives through extracted spatial validation criteria

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentEP2158575B1Detecting haemorrhagic stroke in CT image data
Publication Date: 2018.04.11 PHILIPS INTPROP & STANDARDS GMBH
  • EP2158575B1 patent drawingFigure 1
  • EP2158575B1 patent drawingFigure 2
  • EP2158575B1 patent drawingFigure 3

AI summary

The invention relates to a system (100) arranged to delineate the acute intracerebral haematoma in non-contrasted CT images in two stages. The first stage, performed by the extraction unit (110), employs an analysis of gray values of the image data in order to extract the candidate region. The candidate region may comprise both an acute haematoma and other regions having similar gray values, e.g., regions resulting from partial volume effects at the interface of the bony structures of the skull and the brain. The novel second stage, performed by the classification unit (120), analyzes spatial features of the candidate region such as, for example, the size, shape, and connectedness to the skull bone of the candidate region. Using spatial features of the candidate region improves the correctness of classification of the candidate region as a true or false acute haematoma.