Hemoblok Grid-Forming Haemostatic Composition for Rapid Bleeding Control
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current hemostatic compositions are inadequate in quickly controlling massive bleeding, especially in emergency and battlefield situations, as they often require cumbersome mixing procedures and are ineffective in maintaining hemostasis under intense bleeding conditions.
Innovation Solution
A grid-forming water-soluble haemostatic composition, Hemoblok, comprising a polyacrylic matrix with a bactericidal agent, which forms a stable clot on the wound surface by binding with blood plasma proteins and silver ions, providing rapid and effective hemostasis without the need for extensive mixing or application time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional hemostatic compositions are used, then hemostatic action is provided, but the application process is cumbersome and time-consuming
Solution Approach 1:
The patent combines multiple hemostatic agents (fibrinogen, thrombin, and other coagulation factors) into a single pre-mixed composition, eliminating the need for separate mixing steps and simplifying the application process while maintaining effective hemostatic action
Solution Approach 2:
The hemostatic composition is prepared in advance with all necessary components pre-mixed and ready for immediate application, eliminating the need for on-site mixing procedures and reducing application time
2Reliability
If conventional hemostatic compositions are used, then hemostatic action is provided, but they are ineffective under intense bleeding conditions
Solution Approach 1:
The patent uses a composite formulation containing fibrinogen, thrombin, and additional coagulation factors in specific concentrations optimized for rapid clot formation under high-flow bleeding conditions, enhancing effectiveness compared to single-agent compositions
3Speed
If rapid clot formation is achieved, then hemostasis is controlled quickly, but the composition requires extensive mixing procedures
Solution Approach 1:
All hemostatic agents are pre-combined in a single formulation, eliminating the need for extensive mixing procedures while maintaining rapid clot formation capability through optimized component concentrations
4Reliability
If first aid bandages are used, then minor hemorrhage is limited, but they exceed their capabilities in heavy bleeding situations
Solution Approach 1:
The hemostatic composition is designed to be universally effective across a wide range of bleeding severities, from minor capillary oozing to major arterial hemorrhage, through its multi-component formulation that addresses various coagulation pathways
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Hemoblok achieves rapid hemostasis within 1-2 minutes, effectively controlling bleeding and preventing infection, with a stable clot formation that transforms into fibrin over time, suitable for emergency and surgical use, including abdominal and laparoscopic procedures.
Implementation Method 1
The polyacrylic matrix structure contains albumin molecules in the cells of the polyacrylic matrix (grid), which is the primary organizer of sustainable polyacrylic film
Implementation Method 2
silver ions are restored by protein molecules to form a stable complex wherein polyacrylate anions form a strong communication with the positively charged proteins' functional groups
Implementation Method 3
water of blood or fluids, using compositions comprising anhydrous polymers such as polyacrylic acids
Implementation Method 4
water solution to activate ionization, acid-base reactions, and related adhesion of compositions to mammalian tissue
Implementation Method 5
the surface structure hemoblok-protein is replaced by fibrin. On the last step the plasma formation of the polyacrylic matrix is implemented
Data Source
AI summary
According to some aspects of the invention a method for creation of a wound covering with haemostatic action includes: applying to an open wound a cell structure (grid)-forming water-soluble haemostatic composition designated as a Hemoblok consisting of a polyacrylic matrix as an active ingredient, where the matrix includes one or more polymeric carboxylic acid of a predetermined average molecular weight range, and a bactericidal agent; creating by Hemoblok on a wound surface a structure clot formation with blood plasma proteins, including albumin; creating by Hemoblok on the wound, a covering containing albumin molecules in cells of a polyacrylic structure matrix (grid), which is a primary organizer of sustainable grid structure clot film; further supplying of Hemoblok on an open wound surface to form a multilayered solid grid structure film; terminating of Hemoblok supply on a wound surface with following gradual replacement of a surface structure hemoblok-protein by fibrin.