Hemoglobin Quantification via Reflected Light Correction
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current methods for measuring oxygen saturation of hemoglobin in tissues are limited as they cannot quantify the total hemoglobin amount, leading to incomplete diagnosis and lack of real-time, non-invasive, and non-contact assessment.
Innovation Solution
A hemoglobin quantifying apparatus that acquires light components from two narrow wavelength bands with different reflection characteristics and calculates the hemoglobin amount by correcting these components based on blue and green components, enabling the quantification of both oxygen saturation and total hemoglobin levels.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If pulse oximeter uses transmitted light or scattered light to measure oxygen saturation, then oxygen saturation measurement is achieved, but the device becomes a spatial obstruction during surgery and may cause tissue damage
Solution Approach 1:
The patent introduces a camera as an intermediary device to capture reflected light images instead of using direct contact sensors. The camera system acts as a mediator that obtains oxygen saturation information through non-contact optical reflection, eliminating the need for physical clamps or probes that cause tissue damage and spatial obstruction during surgical procedures
Solution Approach 2:
The patent replaces the mechanical contact-based pulse oximeter system with an optical reflection-based camera system. Instead of using mechanical clamps or probes that physically contact the tissue, the system uses light reflection captured by a camera to measure oxygen saturation, thereby eliminating tissue damage and spatial obstruction while maintaining measurement capability
2Measurement precision
If conventional pulse oximeter measures oxygen saturation at one point, then cardiopulmonary function is reflected, but tissue oxygen metabolism and positional information are not provided
Solution Approach 1:
The patent transitions from one-point measurement to two-dimensional spatial mapping by using a camera to capture reflected light across the entire surgical field. This dimensional expansion provides both oxygen saturation information and positional context, allowing visualization of tissue oxygen metabolism distribution across the surgical area rather than at a single location
Solution Approach 2:
The patent makes the imaging system multi-functional by enabling it to simultaneously provide oxygen saturation measurement, positional information, and tissue oxygen metabolism assessment. The same camera system that captures visual images of the surgical field also extracts physiological information, eliminating the need for separate measurement devices and providing comprehensive diagnostic data
3Measurement precision
If numerical data only is obtained from pulse oximeter, then oxygen saturation value is provided, but intuitive imaging information is lost
Solution Approach 1:
The patent merges quantitative oxygen saturation data with qualitative visual imaging information into a unified system. The camera captures both the visual appearance of tissue and the optical reflection data needed for oxygen saturation calculation, allowing simultaneous display of images and numerical values. This integration provides intuitive visual feedback while maintaining precise measurement capability
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate and detailed diagnosis of tissue oxygen metabolism, blood flow evaluation, tumor delineation, and inflammation assessment by providing real-time imaging and numerical values for hemoglobin oxygen saturation and total hemoglobin amounts.
Implementation Method 1
a light source 15 for irradiating the biological tissue with light at two different wavelengths; a sensor 16 for detecting an intensity of reflected light
Implementation Method 2
The wavelength band of 650 nm to 1000 nm, in which the absorption of oxyhemoglobin and water is minimized, is a region in which light is difficult to be absorbed by a living body
Data Source
AI summary
PROBLEMS The present invention provides the hemoglobin quantifying apparatus which is capable of clearly quantifying the oxygen metabolic state of biological tissue by calculating and quantifying the hemoglobin amount of biological tissue in a non-contact and non-invasive manner.SOLUTION The present invention provides the light receiver unit 2 for receiving any two narrow wavelength band components and white components having reflection characteristics different according to the oxygen saturation of hemoglobin, which are reflected from the biological tissue a, and the hemoglobin amount calculation unit 8 for calculating the hemoglobin amount based on the light components in the two narrow wavelength bands obtained from the received light components, and the hemoglobin amount calculation unit 8 for correcting the light components in the two narrow wavelength bands based on the blue and green components to calculate the hemoglobin amount.