Hemostatic Suture for Arterial Puncture Closure
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current methods for closing arterial punctures often result in tract oozing, necessitating manual compression, as they fail to effectively promote hemostasis at the site of mechanical closure.
Innovation Solution
A tissue puncture closure device with a filament, anchor, sealing tube, and tamping tube, which includes a hemostatic agent or indentation for holding a clot-inducing substance, is used to promote hemostasis by automatically or manually tamping the sealing plug against the anchor, thereby controlling tract oozing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a suture and mechanical closure are deployed to close an arterial puncture, then the puncture is sealed, but tract oozing occurs and manual compression is required
Solution Approach 1:
The patent applies preliminary action by pre-loading the suture with hemostatic substances (thrombogenic materials, clot-inducing agents) before deployment. This ensures that when the suture is placed at the puncture site, the hemostatic agent is already positioned to promote clot formation, eliminating the need for subsequent manual compression to control oozing.
Solution Approach 2:
The patent uses hemostatic substances as intermediaries between the mechanical closure and the tissue. These substances (embedded in the suture or applied via carrier) mediate the interaction between the suture and vascular tissue, promoting localized clot formation and enhancing hemostasis without requiring additional manual intervention.
2Object-affected harmful factors
If manual compression is applied to control tract oozing, then bleeding is controlled, but the procedure time increases and patient discomfort increases
Solution Approach 1:
By pre-equipping the suture with hemostatic agents before the puncture closure, the system eliminates the need for prolonged manual compression. The hemostatic substance begins working immediately upon deployment, reducing the time required to control tract oozing and shorten overall procedure duration.
Solution Approach 2:
The suture with embedded hemostatic substances provides self-service hemostasis at the puncture site. The thrombogenic material on the suture automatically promotes clot formation locally, enabling the system to control tract oozing without requiring continuous manual compression, thereby reducing procedure time and patient discomfort.
3Device complexity
If a simple suture is used for closure, then the device complexity is low, but hemostatic promotion is insufficient
Solution Approach 1:
The patent employs composite materials by combining the suture material with hemostatic substances (thrombogenic agents, clot-inducing materials). This composite structure maintains the mechanical function of the suture while adding hemostatic properties, achieving effective hemostasis promotion without significantly increasing device complexity.
Solution Approach 2:
The patent applies local quality by concentrating hemostatic substances at specific locations on the suture (at the puncture site or along the tract). This localized application of thrombogenic materials ensures effective hemostasis promotion exactly where needed, while keeping the overall device structure simple and avoiding unnecessary complexity throughout the entire suture length.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively reduces or eliminates tract oozing by initiating hemostasis at the puncture site, minimizing the need for manual compression and ensuring immediate vessel closure during procedures like angiographic dye injection and cardiac catheterization.
Implementation Method 1
a thrombogenic substance, hemostatic substance, or clot-producing agent to promote hemostasis
Data Source
AI summary
Apparatus and methods for promoting hemostasis are provided. The apparatuses and methods have particular applicability with tissue puncture closure devices for sealing percutaneous punctures in arteries. In one embodiment, an apparatus for promoting hemostasis a tube having at least one indentation for holding a hemostatic substance. In further embodiments, the apparatus may further include a carrier tube for forming a lid for the indentation, a retractable sheath for forming a lid for the indentation, or a cover for forming a lid of the indentation. In an alternative embodiment the apparatus for promoting hemostasis comprises a suture provided with a hemostatic substance.