Herbal Medicine Extraction via Spray and Counter-Current Precipitation

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Solution Overview

Problem

Current methods for extracting active ingredients from traditional Chinese herbal medicine are inefficient, particularly in terms of time and solvent usage, and are not suitable for continuous production, as they often require fresh solvents and result in low yields and instability of heat-sensitive compounds.

Innovation Solution

A high-pressure spray and counter-current precipitation extraction method using a device with specific components like agitation tanks, plunger pumps, centrifuges, and filter presses, which increases solvent contact with herbs, improves extraction efficiency, and allows for continuous production by recycling solvents and effectively purifying extracts.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If cold extraction method is used, then heat-sensitive active ingredients are preserved, but extraction time is long and solvent usage is large

Engineering Contradiction:
Improvestability of heat-sensitive active ingredientsVSAvoidextraction time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical extraction methods with ultrasonic extraction technology. The ultrasonic device generates high-frequency vibrations that create cavitation bubbles in the solvent, which implode to produce localized high energy that accelerates the extraction process while maintaining low temperature, thus preserving heat-sensitive compounds while reducing extraction time from hours to minutes.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The ultrasonic extraction process utilizes periodic ultrasonic waves that create alternating compression and rarefaction cycles in the solvent. This periodic action generates repeated cavitation events that continuously renew the extraction interface between solvent and herbal material, significantly enhancing mass transfer efficiency and reducing overall extraction time compared to static cold extraction methods.

Inventive Principle:
Principle #19Periodic action

2Productivity

If hot extraction method is used, then extraction time is reduced, but heat-sensitive active ingredients are decomposed

Engineering Contradiction:
Improveextraction efficiencyVSAvoidstability of heat-sensitive active ingredients
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent replaces thermal energy input with mechanical ultrasonic energy. Instead of heating the extraction system to accelerate extraction kinetics, ultrasonic cavitation provides the necessary energy for solvent penetration and compound dissolution through mechanical bubble collapse, achieving high extraction efficiency without thermal degradation of sensitive active ingredients.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of manufacture

If traditional extraction equipment is used, then equipment cost is low, but production is discontinuous and equipment utilization is low

Engineering Contradiction:
Improveequipment costVSAvoidcontinuous production capability
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent designs an integrated extraction system where the ultrasonic device, filtration system, and solvent recovery apparatus form a continuous processing line. The equipment can process multiple batches sequentially without requiring disassembly or cleaning between runs, and the solvent recovery system automatically recycles solvents back to the extraction tank, enabling continuous operation and high equipment utilization while maintaining cost-effectiveness.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method significantly enhances extraction efficiency, reduces solvent usage, and achieves high product recovery rates with uniform quality, enabling continuous production and improved equipment utilization.

Implementation Method 1

spraying countercurrently the precipitation solvent from the bottom of the tube centrifuge to form a precipitation solution, centrifuging the precipitation solution and discharging a supernatant

Methodology Applied
Scientific EffectCentrifugal separation: Centrifugal Separation

Implementation Method 2

pumping the extraction solution to a vacuum concentration tank, concentrating the extraction solution under reduced pressure

Methodology Applied
Scientific EffectVacuum evaporation: Evaporation

Implementation Method 3

spraying countercurrently the precipitation solvent from the bottom of the tube centrifuge to form a precipitation solution

Methodology Applied
Scientific EffectPrecipitation: Precipitation

Data Source

PatentUS11219652B2Method for extracting herbal medicine
Publication Date: 2022.01.11 SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD
  • US11219652B2 patent drawing
  • US11219652B2 patent drawing

AI summary

A method for extracting herbal medicine includes: step one, spray extraction; step two, pressure filtration and concentration; step three, spray and countercurrent precipitation; and step four, concentrating reduced pressure and drying.