Herbal Formulation for Athletic Endurance via Nitric Oxide Boosting

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Solution Overview

Problem

Existing herbal supplements fail to effectively enhance physical endurance and strength in athletes, lacking synergistic formulations and dosing strategies that improve nitric oxide levels, vasodilation, and antioxidant activity.

Innovation Solution

A powdered herbal formulation combining methoxy flavones from Kaempferia parviflora, saponins from Moringa oleifera, and polyphenols from Punica granatum, encapsulated in a natural matrix, to increase nitric oxide levels, inhibit phosphodiesterase activity, and enhance antioxidant activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing herbal supplements are used, then athletes can maintain normal physical performance, but they fail to effectively enhance physical endurance and strength

Engineering Contradiction:
Improvephysical endurance enhancementVSAvoidathletic performance improvement
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent combines three different herbal extracts (Kaempferia parviflora, Moringa oleifera, and Punica granatum) with complementary mechanisms of action into a single synergistic formulation. This merging of multiple natural ingredients with different physiological effects resolves the contradiction by creating a comprehensive supplement that both maintains baseline performance and enhances endurance and strength beyond what single-herb supplements can achieve.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The formulation uses a composite structure combining multiple herbal extracts with specific concentrations (50-70% Kaempferia parviflora, 10-30% Moringa oleifera, 10-30% Punica granatum) encapsulated in a natural matrix. This composite approach allows the supplement to simultaneously provide nitric oxide boosting, antioxidant protection, and anti-fatigue effects, effectively enhancing athletic performance while maintaining reliability.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If herbal supplements are formulated without synergistic combinations, then the formulation is simpler to prepare, but they lack effectiveness in improving physical fitness

Engineering Contradiction:
Improveformulation preparationVSAvoidphysical fitness improvement
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent specifies precise concentration ranges for each herbal extract (Kaempferia parviflora: 50-70%, Moringa oleifera: 10-30%, Punica granatum: 10-30%) and uses encapsulation technology to deliver these parameters consistently. This parameter control ensures the formulation is both manufacturable with clear specifications and effective in improving physical fitness through synergistic interactions at optimized concentrations.

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If antioxidants are not included, then the formulation is simpler, but NO breakdown occurs reducing performance

Engineering Contradiction:
Improveformulation compositionVSAvoidnitric oxide stability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The Punica granatum extract acts as an intermediary protective agent that prevents the breakdown of nitric oxide through its high polyphenol content. This intermediary component mediates between the nitric oxide-boosting Kaempferia parviflora and the overall performance outcome by stabilizing NO levels, resolving the contradiction between formulation simplicity and nitric oxide stability.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of manufacture

If a single herbal extract is used, then the formulation is easier to produce, but it does not provide comprehensive performance enhancement

Engineering Contradiction:
Improveproduction processVSAvoidmuscle strength and stamina improvement
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent creates a multi-functional formulation where each herbal extract contributes different functions: Kaempferia parviflora for nitric oxide boosting and vasodilation, Moringa oleifera for anti-fatigue and energy metabolism, and Punica granatum for antioxidant protection. This universal approach allows a single supplement to provide comprehensive performance enhancement including muscle strength, stamina, and recovery, resolving the contradiction between production simplicity and performance comprehensiveness.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation increases nitrate and nitrite levels, improves physical endurance, reduces oxidative stress, and enhances muscle recovery, without toxicity, by increasing nitric oxide levels and antioxidant activity.

Implementation Method 1

NO also plays a crucial role because of its vasodilation activity in blood vessels as it helps in maintaining the fluid homeostasis and in regulating the blood pressure

Methodology Applied
Scientific EffectVasodilation:

Implementation Method 2

Anti-oxidants also play a crucial role in maintaining the performance of the athletes by preventing breakdown of NO

Methodology Applied
Scientific EffectAntioxidant activity: Oxidation

Implementation Method 3

The formulation increases nitrate and nitrite levels, improves physical endurance, reduces oxidative stress, and enhances muscle recovery

Methodology Applied
Scientific EffectOxidative stress reduction: Oxidation

Implementation Method 4

The formulation increases nitrate and nitrite levels, improves physical endurance... by increasing nitric oxide levels and antioxidant activity

Methodology Applied
Scientific EffectPhosphodiesterase inhibition:

Data Source

PatentEP3500283B1A formulation for improving physical endurance in athletes and a method for preparing the same
Publication Date: 2026.02.18 PLANT LIPIDS
  • EP3500283B1 patent drawingFigure 1~2(b)
  • EP3500283B1 patent drawingFigure 3~4
  • EP3500283B1 patent drawingFigure 5

AI summary

The present invention discloses a herbal formulation in powdered dosage form, which is useful to enhance the physical endurance or strength in athletes. The invention also discloses a method of preparation of the formulation, which involves the encapsulation of the natural ingredients in a natural matrix. The formulation comprises Moringa oleifera, Kaempferia parviflora and Punica granatum that are processed to obtain the product in powder form by encapsulation of the natural ingredients in a natural matrix. The formulation increased the nitrate and nitrite levels in serum and saliva in human and is useful to improve the general health of the athletes.