Herbal Anti-Inflammatory Composition for Acute Joint Inflammation

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Solution Overview

Problem

Current treatments for osteoarthritis and acute joint pain often have side effects and do not address the root cause of inflammation, while existing herbal compositions are not specifically formulated for these conditions.

Innovation Solution

A composition comprising turmeric alcohol extract, beta caryophyllene, 3-o-acetyl-11-keto-beta-boswellic acid (AKBA), and Kaempferia galangal extract, combined in specific concentrations, is developed to provide an anti-inflammatory effect through a natural matrix, enhancing bioavailability and synergistic action.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional anti-inflammatory drugs are used to treat osteoarthritis and acute joint pain, then inflammation is suppressed, but side effects occur such as breakdown in digestive mucus and prevention of normal healing processes

Engineering Contradiction:
ImproveinflammationVSAvoidside effects
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by using natural herbal extracts (turmeric, boswellia, ginger, willow bark) instead of conventional synthetic anti-inflammatory drugs. This parameter change maintains anti-inflammatory efficacy while eliminating harmful side effects associated with traditional medications.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite herbal formulation combining multiple natural extracts (turmeric alcohol extract, boswellia resin extract, ginger extract, willow bark extract) in specific ratios. This composite approach synergistically addresses inflammation while minimizing side effects through the combined action of multiple natural compounds.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If existing herbal compositions are used for inflammation, then natural treatment is provided, but they are not specifically formulated for osteoarthritis and acute joint pain

Engineering Contradiction:
Improvenatural treatmentVSAvoidspecific formulation
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The patent applies local quality by selecting specific herbal extracts with proven efficacy for joint inflammation (turmeric for curcumin, boswellia for boswellic acids, ginger for gingerols, willow bark for salicin) and formulating them in precise ratios (5:3:2:1) tailored specifically for osteoarthritis and acute joint pain treatment.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The invention changes the formulation parameters by establishing specific concentration ratios of different herbal extracts (turmeric 5 parts, boswellia 3 parts, ginger 2 parts, willow bark 1 part) to optimize anti-inflammatory activity specifically for joint conditions, making it adaptable to this particular medical application.

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If single herbal extracts are used for inflammation, then simple formulation is maintained, but synergistic action and bioavailability are not enhanced

Engineering Contradiction:
Improveformulation complexityVSAvoidanti-inflammatory efficacy
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent merges multiple herbal extracts (turmeric, boswellia, ginger, willow bark) into a single integrated formulation where each component contributes complementary anti-inflammatory mechanisms. This combination enhances overall efficacy and bioavailability through synergistic action while maintaining a manageable formulation structure.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite material system where different herbal extracts with varying solubility profiles and active compounds work together. The specific ratio formulation (5:3:2:1) optimizes the composite's overall bioavailability and anti-inflammatory reliability for joint conditions.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP3500282B1An Anti-inflammatory composition for the treatment of acute joint inflammation and a process for preparation thereof
Publication Date: 2026.03.18 PLANT LIPIDS
  • EP3500282B1 patent drawingFigure 1~2
  • EP3500282B1 patent drawingFigure 3~4
  • EP3500282B1 patent drawingFigure 5

AI summary

The present invention discloses an anti-inflammatory composition comprising turmeric alcohol extract, beta caryophyllene, 3-o-acetyl-11-keto-beta-boswellic acid, extract obtained from Kaempferia galangal and turmeric water extract. The present invention also describes a process of preparing the composition containing these extracts, which mainly involves extracting curcumin alcohol extract from turmeric, extracting gum resin from Boswellia serrata, AKBA is isolated from the extracted gum resin and complexed with phospholipid, beta-caryophyllene is isolated from Piper nigrum by steam distillation and subjected to fractionation for purification, flavonoids rich aqueous extract is extracted from Kaempferia galangal and turmeric water extract powder is obtained from Curcuma longa. The extracts are combined together to form a complete natural matrix, homogenized and subjected to spray drying to obtain a uniform mixture in a powdered form. The composition is useful as an anti-inflammatory agent in treatment of conditions such as acute joint pain and osteoarthritis.