Herbal Composition for Kidney Stone Elimination

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Solution Overview

Problem

Current treatments for kidney stones and urinary tract infections often result in significant side effects and difficulties in determining effective doses of herbal remedies, leading to ineffective pain management and incomplete stone elimination.

Innovation Solution

A herbal and pharmaceutical composition comprising Equisetum arvense, Spergularia rubra, Peumus boldus, Opuntia ficus indica, Sideritis angustifolia, Rosmarinus officinalis, Cynodon dactylon, and Melissa officinalis, formulated to inhibit stone formation, increase urine production, and reduce inflammation, thereby facilitating stone elimination and preventing re-formation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional medication therapy is used for kidney stone treatment, then pain relief and stone passing assistance are achieved, but significant side effects occur and drug absorption/metabolism issues arise

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses herbal compositions as temporary, natural alternatives to conventional medications. The herbal blend acts as a short-term intervention that facilitates stone passage and reduces pain without the cumulative side effects of pharmaceutical drugs, allowing the body to return to its natural state after treatment.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent employs a composite herbal formulation combining multiple plant extracts (Uva ursi, Taraxacum, Basil, and other herbs) in specific proportions. This composite approach synergizes the therapeutic effects of individual herbs while balancing their side effects, creating a more effective and safer treatment than single-herb or conventional pharmaceutical approaches.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If herbal remedies are used for kidney stone treatment, then natural therapy is provided, but determining effective doses is difficult and treatment may be ineffective

Engineering Contradiction:
Improvenatural treatmentVSAvoiddose determination
Core Design Contradiction:
Object-affected harmful factorsVSManufacturing precision

Solution Approach 1:

The patent specifies precise parameters for herbal composition including exact weight ratios of each herb (e.g., Uva ursi 20-40%, Taraxacum 15-30%, Basil 10-25%), extraction concentrations, and dosage ranges. This standardization transforms variable herbal remedies into a precisely dosed therapeutic product with reproducible efficacy.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent incorporates monitoring parameters for treatment effectiveness including urine output volume, stone passage confirmation, and symptom resolution timelines. This feedback mechanism allows clinicians to adjust dosing and duration based on patient response, ensuring optimal therapeutic outcomes while minimizing unnecessary herb exposure.

Inventive Principle:
Principle #23Feedback

3Reliability

If high doses of herbs are used to ensure effectiveness, then treatment efficacy improves, but undesired effects occur when daily allowance is exceeded

Engineering Contradiction:
Improvetreatment efficacyVSAvoidundesired effects from excessive dose
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent uses moderate doses of each herb within optimized ranges rather than maximum tolerated doses. For example, Uva ursi is dosed at 20-40% of the total composition rather than higher concentrations that would cause side effects. This partial action approach maintains therapeutic effectiveness while staying below thresholds for adverse reactions.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The patent establishes specific concentration parameters for each herb that balance efficacy and safety. These parameters include extraction solvent ratios, heating temperatures and durations, and final composition concentrations. By controlling these parameters precisely, the patent ensures therapeutic effectiveness is achieved without exceeding safe dosage thresholds.

Inventive Principle:
Principle #35Parameter changes

4Ease of operation

If multiple medications are used for pain relief and stone passage, then comprehensive symptom management is achieved, but drug interactions and increased side effects occur

Engineering Contradiction:
Improvesymptom managementVSAvoiddrug interactions
Core Design Contradiction:
Ease of operationVSObject-generated harmful factors

Solution Approach 1:

The patent combines multiple herbal therapies into a single integrated formulation that addresses multiple symptoms simultaneously. The herb blend includes components for pain relief, stone dissolution, urinary tract anti-inflammation, and muscle relaxation, replacing the need for multiple separate pharmaceutical medications and their associated interactions.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite herbal preparation where synergistic interactions between herbs enhance therapeutic effects while antagonistic interactions are minimized through careful selection and proportioning. For example, anti-inflammatory herbs are combined with analgesic herbs in ratios that enhance pain relief without increasing gastrointestinal side effects.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively reduces stone size, promotes stone elimination, alleviates urinary tract discomfort, and prevents infection and inflammation, with optimized concentrations of active ingredients ensuring improved treatment outcomes for kidney stones and urinary tract infections.

Implementation Method 1

Equisetum arvense... behaves like a slight diuretic... It has a high capacity of removing/eliminating water from body and enables 30% more urination than normal

Methodology Applied
Scientific EffectDiuretic effect:

Implementation Method 2

Spergularia rubra... has diuretic, spasm eliminating, anti-inflammatory, anti-bacterial and antioxidant effects... eases the passing of kidney stones via urinary tract

Methodology Applied
Scientific EffectSpasmolytic effect:

Implementation Method 3

Spergularia rubra... has diuretic, spasm eliminating, anti-inflammatory, anti-bacterial and antioxidant effects

Methodology Applied
Scientific EffectAnti-inflammatory effect:

Implementation Method 4

Spergularia rubra... has diuretic, spasm eliminating, anti-inflammatory, anti-bacterial and antioxidant effects

Methodology Applied
Scientific EffectAnti-bacterial effect:

Data Source

PatentEP3806878B1Herbal compositions for the treatment of urolithiasis and urinary tract infections
Publication Date: 2024.06.05 SETONDA SL
  • EP3806878B1 patent drawing

AI summary

Present invention relates to a herbal composition for the treatment of urolithiasis (kidney stones), and prophylaxis of re-formation of stones after passing them, for the treatment of gout, and for inhibition of excessive amount of salts (urates, oxalates, phosphates, carbonates) in kidneys, for the treatment of dysuria phenomenon (pollakiuria, strangury, dysuria, nycturia, low urinary pressure and urinary continence), and of urinary and biliary tract spasm, spastic colitis, different poisoning types (drugs, alcohol, medications, food poisoning), for the treatment of asymptomatic bacteriuria and for the treatment of urinary tract infections (cystitis, urethritis, pyelonephritis etc.), wherein its production is disclosed by using herbal composition comprising Equisetum arvense at a concentration of 3%-67% by weight, spergularia rubra at a concentration of 2%-38% by weight, peumus boldus at a concentration of 1.5%-32% by weight, opuntia ficus indica at a concentration of 1 %-20% by weight, sideritis angustifolia at a concentration of 1 -20% by weight, rosmarinus officinalis at a concentration of 1-20% by weight, cynodon dactylon at a concentration of 1 -20% by weight and melissa officinalis at a concentration of 1 -20% by weight, and vapor distillation method.