Herbal Vaginal Capsule for Bacterial Vaginosis Treatment
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Solution Overview
Problem
Current treatments for bacterial vaginosis, including pharmaceuticals and traditional Chinese medicine decoctions, face challenges such as high recurrence rates, drug resistance, poor patient compliance, and a lack of effective formulations for this condition.
Innovation Solution
A traditional Chinese herbal composition comprising Zingiberis Rhizoma Recens, Schisandrae Chinensis Fructus, Cinnamomi Cortex, Artemisiae Argyi Folium, Codonopsis Radix, a compound traditional Chinese herbal fermentation broth, Pulsatillae Radix, Lonicerae Japonicae Flos, Taraxaci Herba, Akebiae Caulis, Polygoni Cuspidati Rhizoma et Radix, and Atractylodis Macrocephalae Rhizoma, with the fermentation broth obtained by fermenting Sophorae Flavescentis Radix, Artemisiae Annuae Herba, Eucommiae Cortex, and Coptidis Rhizoma with Lactobacillus acidophilus, is developed to address bacterial vaginosis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If pharmaceuticals are used to treat bacterial vaginosis, then antibacterial effect is improved, but drug resistance occurs and recurrence rate increases
Solution Approach 1:
The patent uses a composite traditional Chinese medicine formula containing 12 different herbal components (Zingiberis Rhizoma Recens, Schisandrae Chinensis Fructus, Cinnamomi Cortex, Artemisiae Argyi Folium, Codonopsis Radix, Pulsatillae Radix, Lonicerae Japonicae Flos, Taraxaci Herba, Akebiae Caulis, Polygoni Cuspidati Rhizoma et Radix, Atractylodis Macrocephalae Rhizoma, and compound fermentation broth) to treat bacterial vaginosis. This multi-component herbal composition provides broad-spectrum antibacterial activity against pathogenic bacteria while maintaining low toxicity and avoiding drug resistance, thereby resolving the contradiction between effective treatment and harmful side effects.
2Reliability
If TCM decoctions are used to treat bacterial vaginosis, then therapeutic effect is improved, but patient compliance deteriorates due to bitter taste and high dose
Solution Approach 1:
The patent transforms the traditional TCM decoction from liquid form to solid capsule form through extraction and concentration processes. The extracted active components are encapsulated, which eliminates the bitter taste and improves ease of administration. Patients can take the capsules orally with water, significantly improving compliance while maintaining the therapeutic effects of the original herbal formula.
3Reliability
If TCM gynecological lotions are used to treat bacterial vaginosis, then anti-inflammatory effect is improved, but applicability for bacterial vaginosis specifically is insufficient
Solution Approach 1:
The patent develops a vaginal capsule formulation specifically designed for local application in the vaginal cavity. The capsule contains herbal components that are released locally at the site of infection, providing targeted antibacterial and anti-inflammatory effects for bacterial vaginosis. This localized delivery system enhances the adaptability and specificity of the treatment for this particular condition while maintaining the anti-inflammatory benefits of TCM.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The herbal composition significantly inhibits pathogenic bacteria like Gardnerella vaginalis and Bacteroides vulgatus, promotes beneficial vaginal microbiota, and provides a safe, effective, and long-lasting antibacterial effect, improving patient outcomes and compliance.
Implementation Method 1
The compound traditional Chinese herbal fermentation broth is obtained by fermenting Sophorae Flavescentis Radix, Artemisiae Annuae Herba, Eucommiae Cortex, and Coptidis Rhizoma with Lactobacillus acidophilus
Data Source
AI summary
The present disclosure relates to the technical field of traditional Chinese herbal composition, and in particular to a traditional Chinese herbal composition for the treatment of bacterial vaginosis and a preparation method thereof. The traditional Chinese herbal composition for the treatment of bacterial vaginosis provided by the present disclosure is prepared from the following components in parts by weight: 40-50 parts of Zingiberis Rhizoma Recens, 35-45 parts of Schisandrae Chinensis Fructus, 30-40 parts of Cinnamomi Cortex, 30-40 parts of Artemisiae Argyi Folium, 25-35 parts of Codonopsis Radix, 25-35 parts of a compound traditional Chinese herbal fermentation broth, 20-30 parts of Pulsatillae Radix, 20-25 parts of Lonicerae Japonicae Flos, 15-20 parts of Taraxaci Herba, 15-20 parts of Akebiae Caulis, 10-15 parts of Polygoni Cuspidati Rhizoma et Radix, and 5-10 parts of Atractylodis Macrocephalae Rhizoma.