Herbicidal Composition with Auxin Transport Inhibitor

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Solution Overview

Problem

Current herbicides are inadequate in effectively controlling undesirable vegetation in agricultural settings, as they often require multiple applications and can lead to herbicide resistance in weeds.

Innovation Solution

A herbicidal composition combining 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or its agriculturally acceptable ester or salt with an auxin transport inhibitor, such as chlorflurenol-methyl, diflufenzopyr, flurenol, or naptalam, applied at various ratios to enhance weed control efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional herbicides are used to control undesirable vegetation, then weed control is achieved, but multiple applications are required and herbicide resistance develops in weeds

Engineering Contradiction:
Improveweed control efficacyVSAvoidnumber of applications
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent combines two herbicides with different modes of action (formula I compound and auxin transport inhibitor) into a single application composition. This merging allows simultaneous activation of multiple herbicidal mechanisms, achieving superior weed control in one application rather than requiring multiple separate applications, thereby resolving the contradiction between reliability and time loss

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If conventional herbicides are used to control undesirable vegetation, then weed control is achieved, but herbicide resistance in weeds increases

Engineering Contradiction:
Improveweed control efficacyVSAvoidherbicide resistance
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

By merging two herbicides with different modes of action (formula I compound targeting multiple pathways including ACCase and HPPD, and auxin transport inhibitor targeting auxin signaling), the patent creates a combination that reduces selective pressure on any single target site. This diversifies the herbicidal mechanism, making it harder for weeds to develop resistance to both components simultaneously, thereby addressing the herbicide resistance problem

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If higher herbicide doses are applied to improve weed control, then efficacy increases, but environmental impact and cost increase

Engineering Contradiction:
Improveweed control efficacyVSAvoidherbicide application rate
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The combination of formula I compound and auxin transport inhibitor exhibits synergistic or additive effects where the combined efficacy exceeds that of individual herbicides at the same dose. This allows achieving superior weed control at lower total application rates, reducing both environmental impact and cost while maintaining or improving efficacy

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent optimizes the ratio of the two herbicide components (formula I compound to auxin transport inhibitor) to achieve maximum efficacy at minimum cost. By adjusting this parameter ratio, the formulation achieves superior weed control with reduced total herbicide load, addressing the contradiction between efficacy and substance loss

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS8883682B2Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and auxin transport inhibitors
Publication Date: 2014.11.11 CORTEVA AGRISCIENCE LLC
  • US8883682B2 patent drawing
  • US8883682B2 patent drawing
  • US8883682B2 patent drawing

AI summary

Provided herein are herbicidal composition containing and method of controlling undesirable vegetation utilizing (a) a compound of formula (I):or an agriculturally acceptable salt or ester thereof and (b) an auxin transport inhibitor. Exemplary auxin transport inhibitors include chlorflurenol-methyl, diflufenzopyr, flurenol and naptalam, or an agriculturally acceptable derivative thereof. The methods and compositions described herein provide control of undesirable vegetation, e.g., in rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, vegetables, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crop, industrial vegetation management (IVM) or rights of way (ROW).