Herbicidal Composition Combining Metamitron and Bixlozone

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Solution Overview

Problem

Current herbicides often lead to weed resistance and unsatisfactory control, with many combinations failing to achieve synergistic effects, resulting in reduced efficacy and potential toxicological and environmental issues.

Innovation Solution

A herbicidal composition comprising metamitron, bixlozone, and at least one herbicide from the groups of oxyacetamides, thiocarbamates, or urea inhibitors of photosynthesis at PS II, which can be used alone or in combination with adjuvants, to enhance weed control through synergistic effects, reduced dosage, and prolonged activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If repeated and exclusive application of an individual active ingredient is used to control weeds, then control effectiveness is initially good, but weed resistance develops leading to loss of control effectiveness

Engineering Contradiction:
Improveweed control effectivenessVSAvoidweed resistance development
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines three different herbicides with distinct modes of action (metamitron - amino acid synthesis inhibitor, bixlozone - photosystem II inhibitor, and sulfonylurea - enzyme inhibitor) into a single composition. This merging of multiple active ingredients with different mechanisms prevents weed resistance by attacking multiple biological pathways simultaneously, making it difficult for weeds to develop adaptive resistance to any single ingredient.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite herbicidal formulation containing multiple chemically distinct active ingredients (metamitron, bixlozone, and sulfonylurea) along with adjuvants and carriers. This composite structure provides synergistic effects where the combination of ingredients produces greater control effectiveness than individual components alone, while also managing resistance through mechanistic diversity.

Inventive Principle:
Principle #40Composite materials

2Reliability

If combinations of herbicides are used to broaden spectrum of control and minimize doses, then control effectiveness improves, but achieving synergistic effects is rare and formulation complexity increases

Engineering Contradiction:
Improveweed control effectivenessVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent optimizes specific concentration parameters of each active ingredient (metamitron at 10-500 g/ha, bixlozone at 10-200 g/ha, sulfonylurea at 10-500 g/ha) to achieve synergistic effects. By carefully controlling these quantitative parameters and their ratios, the formulation achieves enhanced control effectiveness while managing the complexity through defined concentration ranges rather than arbitrary combinations.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The formulation includes adjuvants and carriers that act as intermediaries to facilitate the interaction between the three active ingredients. These intermediary substances help maintain stability, improve solubility, and enhance the synergistic interactions between metamitron, bixlozone, and sulfonylurea, thereby achieving effective weed control without excessive formulation complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If higher doses of herbicides are applied to overcome resistance, then control effectiveness is maintained, but toxicological and environmental effects increase

Engineering Contradiction:
Improveweed control effectivenessVSAvoidtoxicological and environmental effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies lower doses of each individual herbicide component compared to using a single herbicide at high dose. The synergistic interaction between metamitron, bixlozone, and sulfonylurea allows each ingredient to work at sub-optimal individual doses while collectively achieving superior control effectiveness. This partial action of multiple ingredients reduces the toxicological and environmental burden compared to excessive dosing of a single agent.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentEP4295687A1Agrochemical herbicidal composition
Publication Date: 2023.12.27 ADAMA AGAN LTD
  • EP4295687A1 patent drawing
  • EP4295687A1 patent drawing
  • EP4295687A1 patent drawing

AI summary

A combination of herbicidal active ingredients for agricultural applications, tank mixes, methods for controlling weeds, and kits-of-parts comprising herbicidal active ingredients and an instruction manual comprising instructions to admix the components before being used.