Herbicidal Compositions With Safeners for Crop Tolerance

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Solution Overview

Problem

Existing herbicidal compositions exhibit unfavorable biological properties, such as herbicidal action, tolerance by crop plants, and toxicological and ecotoxicological issues.

Innovation Solution

Development of herbicidal compositions comprising a specific N-(1,3,4-oxadiazol-2-yl)arylcarboxamide compound with absolute configuration (component A) and one or more herbicides (component B) selected from groups B1, B2, B5, B6, B8, and B9, optionally combined with safeners (component C) like benoxacor or cyprosulfamide, applied in various formulations for pre- and post-emergence weed control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing N-(1,3,4-oxadiazol-2-yl)arylcarboxamide herbicidal compositions are used, then herbicidal activity is achieved, but unfavorable biological properties including poor crop plant tolerance and toxicological issues occur

Engineering Contradiction:

Improveherbicidal actionVSAvoidphytotoxicity to crop plants

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by specifying a particular absolute configuration (enantiomer or diastereomer) of the N-(1,3,4-oxadiazol-2-yl)arylcarboxamide compound. This stereochemical parameter change results in improved crop plant tolerance while maintaining herbicidal activity, directly resolving the contradiction between herbicidal efficacy and phytotoxicity

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent combines the specific enantiomer or diastereomer of N-(1,3,4-oxadiazol-2-yl)arylcarboxamide with safeners (such as benoxacor, cyprosulfamide, or dichlormid) to create a composite herbicidal composition. This composite approach enhances crop plant tolerance through synergistic protection while maintaining effective weed control

Inventive Principle:

Principle #40Composite materials

2Reliability

If existing herbicidal compositions are used, then weed control is achieved, but unfavorable toxicological and ecotoxicological properties occur

Engineering Contradiction:

Improveweed control efficacyVSAvoidtoxicological and ecotoxicological properties

Core Design Contradiction:

ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the stereochemical parameter of the herbicidal composition by using a specific enantiomer or diastereomer of the N-(1,3,4-oxadiazol-2-yl)arylcarboxamide compound. This parameter change improves the toxicological and ecotoxicological profile while preserving herbicidal efficacy against weeds

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent converts the potential harm of racemic or mixed stereoisomer compositions into benefit by isolating and using only the beneficial enantiomer or diastereomer. This selective approach eliminates or reduces toxicological and ecotoxicological issues while maintaining or improving weed control effectiveness

Inventive Principle:

Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS20260068885A1Herbicidal compositions

Publication Date: 2026.03.12 BAYER AG

AI summary

Herbicidal compositions are described, comprising an N-(1,3,4-oxadiazol-2-yl)arylcarboxamide and further herbicides.