Herbicidal Compounds Selective Weed Control
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Solution Overview
Problem
Current herbicidal compounds for controlling weeds in crops are limited in their effectiveness and specificity, leading to challenges in selectively targeting and inhibiting plant growth without harming desired crops.
Innovation Solution
Development of novel herbicidal compounds of Formula (I), specifically N-(Tetrazol-5-yl) and N-(Triazol-5-yl) arylcarboxamides, which are designed to selectively target weeds by inhibiting plant growth through specific chemical structures and formulations, including agronomically acceptable salts and herbicidal compositions with formulation adjuvants.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional herbicidal compounds are used to control weeds, then weed control is achieved, but selectivity and specificity are limited leading to harm to desired crops
Solution Approach 1:
The patent applies local quality by creating herbicidal compounds with specific molecular structures (Formula I) that have particular chemical properties enabling selective action. The compounds contain specific substituents (R1-R5, A1a-A4) that conferweed-selective activity, allowing the herbicide to affect weeds differently than crops. This molecular-level differentiation enables effective weed control while protecting desired crops from harm.
Solution Approach 2:
The patent utilizes parameter changes by systematically varying chemical parameters (substituents, molecular weight, functional groups) to optimize herbicidal activity and selectivity. By adjusting parameters such as the type of arylcarboxamide group, tetrazole or triazole ring structure, and various substituents (halogenated, alkyl, alkoxy), the compound's biological activity and specificity are fine-tuned to achieve effective weed control with reduced crop damage.
2Reliability
If herbicidal compounds with higher specificity are developed, then selectivity improves, but compound complexity and development difficulty increase
Solution Approach 1:
The patent applies segmentation by dividing the herbicidal compound into distinct functional modules: a core arylcarboxamide structure, a tetrazole or triazole ring system, and various substituents (R1-R5). Each segment contributes specific properties, allowing independent optimization of different aspects such as binding affinity, selectivity, and metabolic stability. This modular approach facilitates systematic design while managing overall complexity.
Solution Approach 2:
The patent employs universality by creating a versatile chemical framework (Formula I) that can generate multiple herbicidal compounds through variation of substituents. The core structure serves multiple functions: providing the basic herbicidal activity, enabling selectivity through specific groups, and allowing for optimization of different properties by changing R1-R5. This multi-functional design reduces the need for entirely new molecular architectures for different applications.
Data Source
AI summary
The present invention relates to compounds of Formula (I); or an agronomically acceptable salt of said compounds wherein A1a, A1b, A2, A3, A4, X, R1 and R2 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), and to their use for controlling weeds, in particular in crops of useful plants.