Herbicidal Oil Dispersion Stability via Segmented Solvent System

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Solution Overview

Problem

Combining fluroxypyr and sulfonylurea herbicides into a single stable formulation has been challenging due to their differing chemical, biological, and physicochemical properties, leading to instability and degradation issues, particularly with sulfonylureas like metsulfuron methyl, which affects storage stability and compatibility.

Innovation Solution

An oil dispersion comprising a non-aqueous solvent system with metsulfuron methyl as a sodium salt suspended and fluroxypyr-meptyl dissolved, using isobornyl acetate as a solvent that maintains stability, prevents settling, and allows for easy resuspension, while avoiding compatibility issues and enabling the inclusion of additional adjuvants.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If fluroxypyr and sulfonylurea herbicides are combined into a single formulation, then convenience for end users and weed control spectrum are improved, but storage stability and chemical compatibility deteriorate due to differing physicochemical properties

Engineering Contradiction:
Improveweed control spectrumVSAvoidstorage stability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The formulation segments the herbicide components into distinct functional phases: fluroxypyr-meptyl dissolved in aromatic hydrocarbon solvent forms the continuous oil phase, while metsulfuron methyl is suspended as discrete particles. This segmentation allows each component to maintain its optimal chemical environment, preventing degradation while enabling combined application.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The aromatic hydrocarbon solvent acts as an intermediary medium that dissolves fluroxypyr-meptyl and suspends metsulfuron methyl particles, facilitating compatibility between the two herbicides. The solvent system mediates the interaction between components with differing solubility requirements, maintaining formulation stability during storage.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If metsulfuron methyl is formulated in liquid formulations, then ease of application is improved, but hydrolysis and degradation increase due to chemical instability

Engineering Contradiction:
Improveease of applicationVSAvoidchemical stability
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The formulation changes the physical state of metsulfuron methyl from dissolved to suspended particulate form, and uses a non-aqueous aromatic hydrocarbon solvent system. This parameter change reduces water availability for hydrolysis reactions while maintaining liquid formulation properties for easy application and mixing.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If aromatic hydrocarbon solvents are used to enhance fluroxypyr penetration, then herbicide efficacy is improved, but sulfonylurea degradation is accelerated due to chemical incompatibility

Engineering Contradiction:
Improveherbicide efficacyVSAvoidchemical compatibility
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The formulation applies local quality by providing different micro-environments for each herbicide: fluroxypyr-meptyl is dissolved in the aromatic hydrocarbon continuous phase where it can penetrate leaf waxes effectively, while metsulfuron methyl is suspended as particles protected from direct contact with the solvent, reducing degradation while maintaining penetration efficacy.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation exhibits excellent physical stability, ease of application, high biological effectiveness, and crop compatibility, with improved chemical stability and reduced sedimentation, effectively delivering the herbicides without decomposition.

Implementation Method 1

metsulfuron methyl as a sodium salt suspended in the solvent system

Methodology Applied
Scientific EffectSuspension: Suspension

Implementation Method 2

fluroxypyr-meptyl, dissolved in the solvent system

Methodology Applied
Scientific EffectDissolution: Solvation

Implementation Method 3

SUs are known to be unstable as they have a tendency to hydrolyse via cleavage at the sulfonylurea bridge

Methodology Applied
Scientific EffectHydrolysis prevention: Hydrolysis

Data Source

PatentEP3236750B1Herbicidal oil dispersion
Publication Date: 2019.10.30 MITSUI AGRISCI INT S A NV

AI summary

The present invention provides a herbicidal oil dispersion comprising: a non-aqueous solvent system; a sulfonylurea, as the alkali metal salt or alkaline earth metal salt thereof, suspended in the non-aqueous solvent system; and at least one of fluroxypyr, fluroxypyr-meptyl, or fluroxypyr- butoxypropyl dissolved in the non-aqueous solvent system. The invention also relates to the use of isobornyl acetate for suspending the alkali metal salt or alkaline earth metal salt of a sulfonylurea in a herbicidal oil dispersion.