Hermetic Package for Implantable Neural Stimulation Device
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Solution Overview
Problem
Existing implantable neural stimulation devices for vision restoration are bulky and unable to provide adequate simulated vision, requiring a more compact and stable solution for electrical stimulation of retinal cells to effectively aid the visually impaired.
Innovation Solution
A hermetic package design featuring a ceramic substrate with biocompatible metal vias, flip-chip bonded circuits, and a laser-welded metal lid, integrated with a flexible electrode array and secondary inductive coil, minimizing size and promoting healing, while maintaining a secure and functional implantation within the eye.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Volume of moving object
If early prosthetic devices were used for retinal stimulation, then electrical stimulation of retinal cells could be achieved, but the devices were large and bulky
Solution Approach 1:
The patent implements a nested structure where the electrode array is integrated within a compact hermetic package that contains the electronics. The electrode array folds into a compact configuration within the package, allowing the stimulation function to be contained in a much smaller volume while maintaining all necessary components for effective retinal stimulation.
Solution Approach 2:
The electrode array is designed to fold along multiple axes, transitioning from a potentially large flat configuration to a compact three-dimensional folded structure. This dimensional transformation allows the device to maintain its functional electrode surface area while reducing its overall volume significantly for implantation.
2Reliability
If early prosthetic devices were used for retinal stimulation, then electrical stimulation could be provided, but the devices could not produce adequate simulated vision
Solution Approach 1:
The device is segmented into distinct functional modules: a flexible electrode array with multiple independently controllable electrodes, a hermetic package containing electronics for pulse generation and control, and integration components. This segmentation allows for precise control of stimulation patterns to produce adequate simulated vision while managing device complexity through modular design.
Solution Approach 2:
The hermetic package serves multiple functions: it provides hermetic sealing for the electronics, houses the pulse generation circuitry, contains the electrode array in a compact folded configuration, and provides structural support for implantation. This multi-functionality reduces the need for separate components, managing overall device complexity while enabling effective vision restoration.
3Volume of moving object
If a compact implant design is implemented, then device size is reduced, but manufacturing precision requirements increase
Solution Approach 1:
The hermetic package utilizes composite construction with a ceramic substrate providing rigid support and sealing surfaces, combined with metal components for structural integrity and biocompatibility. This composite approach enables precise hermetic sealing in a compact package, as the ceramic provides dimensional stability and precise mating surfaces while the metal components provide flexible sealing interfaces.
Solution Approach 2:
The patent employs specific material property changes and dimensional parameters to achieve hermetic sealing in a compact package. The ceramic substrate thickness, metal lid dimensions, and bonding interface geometries are precisely controlled during manufacturing to ensure hermetic sealing without requiring excessive package size. Thermal and mechanical parameter control during assembly ensures precise fitting of hermetic components.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The design allows for a miniaturized, stable, and biocompatible implant that effectively stimulates retinal cells, reducing obstruction and promoting tissue integration, thereby enhancing vision restoration for individuals with blindness due to photoreceptor degenerative diseases.
Implementation Method 1
A package for an implantable neural stimulation device includes a secondary inductive coil
Implementation Method 2
laser-welded metal lid
Data Source
AI summary
An implantable device having a biocompatible hermetic package made from a biocompatible electrically non-conductive substrate and a cover bonded to the substrate. In integrated circuit and passive circuits all bonded directly to the substrate.