Hexyldecanol for Skin Texture Area Fraction Reduction

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Skin aging leads to a reduction in the stratum corneum's turnover rate, causing a thinner barrier that allows harmful stimuli to penetrate, resulting in visible fine lines and wrinkles, and micro-texture issues on the skin surface.

Innovation Solution

Topical application of hexyldecanol compositions to improve facial skin texture by preventing, delaying, or reducing the appearance of fine lines and wrinkles, potentially through stimulating hyaluronic acid production and enhancing the skin's barrier function.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Shape

If topical treatments are applied to improve skin texture, then the appearance of fine lines and wrinkles is reduced, but the stratum corneum turnover rate remains reduced in aged skin

Engineering Contradiction:
Improveskin surface textureVSAvoidstratum corneum turnover rate
Core Design Contradiction:
ShapeVSProductivity

Solution Approach 1:

Hexyldecanol serves as an intermediary substance that penetrates the stratum corneum barrier and stimulates hyaluronic acid production in the dermis, thereby improving skin texture from within rather than attempting to directly accelerate the slowed cellular turnover process in aged skin

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the approach from modifying cellular turnover parameters to modifying extracellular matrix parameters by increasing hyaluronic acid content, which directly affects skin hydration, plumpness, and texture without relying on accelerated cell division

Inventive Principle:
Principle #35Parameter changes

2Reliability

If the stratum corneum barrier is thickened to prevent harmful penetration, then protection against UV damage and toxins is improved, but the visible appearance of fine lines and wrinkles increases due to thinner effective barrier

Engineering Contradiction:
Improvebarrier protection functionVSAvoidskin surface smoothness
Core Design Contradiction:
ReliabilityVSShape

Solution Approach 1:

The invention shifts the protective mechanism from a purely surface-level barrier (stratum corneum thickness) to a volumetric approach by stimulating hyaluronic acid production in the dermis, creating hydration and structural support from within that simultaneously protects and smooths the skin surface

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentEP2640347B1Improvement of the appearance of fine lines and wrinkles
Publication Date: 2018.03.21 PROCTER & GAMBLE CO
  • EP2640347B1 patent drawingFigure 1
  • EP2640347B1 patent drawing
  • EP2640347B1 patent drawing

AI summary

A method of improving the appearance of facial texture may comprise the step of applying a composition comprising an effective amount of a material that regulates hyaluronic acid synthesis to an area of textured facial skin, wherein the composition is applied for a period of time sufficient for the material to improve the appearance of the facial texture. In some embodiments, the material that regulates hyaluronic acid synthesis is hexyldecanol. The method may also include the step of identifying facial texture on a facial skin surface. In particular embodiments, the facial skin texture is selected from the group consisting of macro-texture, micro-texture, and combinations thereof.