HFC-143 Fluorination Using Chlorinated Feedstocks for High Selectivity

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Solution Overview

Problem

Conventional methods for producing 1,1,2-trifluoroethane (HFC-143) are costly due to the use of expensive starting materials and have low selectivity for HFC-143 as a by-product, with PTL 1 requiring expensive chlorotrifluoroethylene (CTFE) and PTL 2 achieving only 1.9% selectivity.

Innovation Solution

A method involving fluorination reactions of chlorine-containing compounds like 1,1,2-trichloroethane (HCC-140), 1,2-dichloro-1-fluoroethane (HCFC-141), and others with hydrogen fluoride, using a molar ratio over 40, and a chromium-based catalyst at temperatures between 150 to 600°C, to produce HFC-143 efficiently.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chlorotrifluoroethylene (CTFE) is used as starting material for hydrogenation reaction, then HFC-143 can be produced, but the production cost becomes expensive

Engineering Contradiction:
ImproveHFC-143 production capabilityVSAvoidproduction cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent replaces expensive CTFE with cheaper chlorine-containing compounds (1,1,2-trichloroethane, 1,2-dichloro-1-fluoroethane, 1,1-dichloro-2-fluoroethane, or their mixtures) as starting materials. These cheaper substitutes enable cost-effective production of HFC-143 through fluorination reactions with hydrogen fluoride, directly resolving the cost issue while maintaining production capability.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent changes the chemical parameters of the starting material from fluorinated compounds (CTFE) to chlorinated compounds (HCC-140, HCFC-141, HCFC-141a). This parameter change in molecular composition allows the use of cheaper raw materials while achieving the same target product through different reaction pathways (fluorination instead of hydrogenation).

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If fluorination reaction is performed with molar ratio of HF to chlorine-containing compound over 40, then HFC-143 selectivity is improved, but hydrogen fluoride consumption increases

Engineering Contradiction:
ImproveHFC-143 selectivityVSAvoidhydrogen fluoride consumption
Core Design Contradiction:
Manufacturing precisionVSQuantity of substance

Solution Approach 1:

The patent optimizes the molar ratio parameter of HF to chlorine-containing compound to be over 40 (preferably 50-100). This parameter change dramatically improves HFC-143 selectivity from the conventional 1.9% to over 90%, achieving high manufacturing precision. The high HF ratio ensures complete fluorination and suppresses side reactions, directly resolving the selectivity issue.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If conventional fluorination method is used to produce HFC-143 as by-product, then other refrigerants can be produced, but HFC-143 selectivity remains low at 1.9%

Engineering Contradiction:
Improverefrigerant production capabilityVSAvoidHFC-143 selectivity
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent uses chlorine-containing compounds (HCC-140, HCFC-141, HCFC-141a) that can serve multiple purposes. These compounds are not only starting materials for HFC-143 production but also intermediates for other refrigerants. By optimizing the fluorination conditions (HF molar ratio > 40), the process achieves high HFC-143 selectivity while maintaining the versatility to produce other refrigerants, resolving the contradiction between adaptability and manufacturing precision.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method produces HFC-143 at lower costs and with higher efficiency compared to conventional methods, achieving improved selectivity and conversion rates.

Implementation Method 1

the one or more fluorination reactions are performed in the presence of a catalyst in a gas phase... wherein the catalyst is at least partly a chromium-based catalyst

Methodology Applied
Scientific EffectCatalysis: Catalysis

Data Source

PatentEP3851431B1Method for producing 1,1,2-trifluoroethane (HFC-143)
Publication Date: 2025.12.03 DAIKIN INDUSTRIES LTD

AI summary

The present disclosure provides a method for producing HFC-143 that is not expensive, and that is more efficient than conventional methods. Specifically, the present disclosure provides a method for producing 1,1,2-trifluoroethane (HFC-143) that includes contacting at least one chlorine-containing compound selected from the group consisting of 1,1,2-trichloroethane (HCC-140), 1,2-dichloro-1-fluoroethane (HCFC-141), 1,1-dichloro-2-fluoroethane (HCFC-141a), (E,Z)-1,2-dichloroethylene (HCO-1130(E,Z)), and (E,Z)-1-chloro-2-fluoroethylene (HCFO-1131(E,Z)) with hydrogen fluoride to perform one or more fluorination reactions, thereby obtaining a reaction gas containing HFC-143, hydrogen chloride, and hydrogen fluoride.