High-density lattice stent for aneurysm reconstruction
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Solution Overview
Problem
Current endovascular interventions for aneurysms using stent-assisted coiling face issues such as compression of peritumoral brain tissue and nerves, low occlusion density, and high recurrence rates, with the risk of aneurysm rupture due to the mass effect and piercing of the coil through the aneurysmal wall.
Innovation Solution
A surgical apparatus comprising a self-expanding stent with a high-density lattice structure, delivered via a delivery guide wire and microcatheter, which reconstructs the arterial wall by changing blood flow direction and providing a supportive mesh for endothelial cell growth, ensuring dense embolization and minimizing rupture risk.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a coil is used for aneurysm embolization, then the aneurysm cavity can be filled, but the coil causes mass effect compressing peritumoral brain tissue and nerves
Solution Approach 1:
The patent introduces a stent as an intermediary device placed in the parent artery before coil embolization. This stent acts as a mediator that redirects blood flow away from the aneurysm sac while maintaining parent artery patency, thereby reducing the mass effect of coils on surrounding brain tissue and nerves while still achieving effective aneurysm occlusion
2Reliability
If a coil is used for aneurysm embolization, then the aneurysm cavity can be filled, but the occlusion density is low and recurrence rate is high
Solution Approach 1:
The patent applies preliminary action by deploying a stent into the parent artery before coil embolization. This pre-positioned stent creates a scaffold that guides and concentrates coil placement within the aneurysm sac, enabling higher coil packing density and more complete occlusion, thereby reducing recurrence rates
3Reliability
If a coil is used for aneurysm embolization, then the aneurysm cavity can be filled, but the coil head can easily pierce the thin aneurysmal wall causing rupture
Solution Approach 1:
The patent implements beforehand cushioning by placing a stent in the parent artery prior to coil embolization. This stent creates a protective barrier and structural support system that prevents coil herniation and piercing of the thin aneurysmal wall during the embolization process, thereby preventing intraoperative or postoperative aneurysm rupture
4Reliability
If a stent with high coverage rate is used to reconstruct arterial wall, then blood flow direction can be changed to protect aneurysm, but the stent structure becomes more complex
Solution Approach 1:
The patent applies local quality by designing a stent with non-uniform lattice structure where the coverage rate varies at different locations. Specifically, the stent has higher coverage rate at the aneurysm site to redirect blood flow and protect the aneurysm, while maintaining lower coverage in other segments to preserve natural blood flow patterns, thus achieving effective vascular reconstruction without excessive overall complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The apparatus achieves effective vascular reconstruction, reduces recurrence, and maintains the parent artery open by using a high-density lattice stent with a non-uniform structure at the aneurysm site, promoting intima growth and anatomical healing.
Implementation Method 1
reconstructs the arterial wall by changing blood flow direction
Implementation Method 2
providing a supportive mesh for endothelial cell growth, promoting intima growth and anatomical healing
Data Source
Figure 1
Figure 2
Figure 3~5(b)
AI summary
The present application discloses a surgical apparatus for aneurysms comprising: a stent, a delivery guide wire, an introducer sheath and a microcatheter, wherein: the stent is a self-expanding stent; the delivery guide wire outside of which the stent is restrained to is provided in a lumen of the introducer sheath; the introducer sheather is connected with the microcatheter, with lumens communicating, to form a passageway through which the delivery guide wire and the stent are delivered into a human body. The surgical apparatus for aneurysms provided in the examples of the present application is able to deliver and release the stent which has high density and is super soft to a vascular lesion. A lattice structure of the stent is of high coverage at the vascular lesion such that the stent released into the vessel produces the same effects as healing of parent vessel, and thus improves the treatment of vascular aneurysms.