High Flow Oxygen Therapy with On-Demand Humidification

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Solution Overview

Problem

Current systems for delivering high flow oxygen to subjects with respiratory diseases, such as COPD, are often bulky, uncomfortable due to excessive drying of the oro-nasal and upper airways, and fail to effectively address Expiratory Flow Limitation (EFL).

Innovation Solution

A system comprising an oxygen concentrator, an aerosol generator, and an exhalation valve, which delivers a humidified flow of concentrated oxygen through a small diameter tube, providing positive expiratory pressure and reducing CO2 rebreathing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high flow rate oxygen therapy is delivered to subjects with respiratory diseases, then blood oxygenation is improved, but the oro-nasal and upper airways experience excessive drying

Engineering Contradiction:
Improveblood oxygenationVSAvoiddrying of oro-nasal and upper airways
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

A water vaporizer is introduced as an intermediary device between the oxygen source and the subject. The water vaporizer generates water vapor that is mixed with the high flow rate oxygen therapy, thereby humidifying the gas stream without compromising the oxygen delivery effectiveness. This mediator approach allows simultaneous achievement of improved blood oxygenation and prevention of airway drying.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If conventional humidification systems are used with high flow oxygen, then humidity is provided, but the systems become large and bulky

Engineering Contradiction:
Improvehumidity provisionVSAvoidhumidification system size
Core Design Contradiction:
Object-affected harmful factorsVSVolume of moving object

Solution Approach 1:

The patent replaces conventional mechanical humidification systems (which use heat exchangers, reservoirs, and complex vapor generation mechanisms) with a simplified water vaporizer system. This substitution maintains the essential humidification function while dramatically reducing the system's size and complexity, making it suitable for portable high flow oxygen therapy applications.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If high flow rate oxygen is delivered through conventional systems, then oxygen therapy is effective, but comfort is reduced due to bulk and drying effects

Engineering Contradiction:
Improveoxygen therapy effectivenessVSAvoidsubject comfort
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent merges the oxygen delivery function and the humidification function into a single integrated system. By combining the high flow oxygen generator and water vaporizer into one unified device with a compact design, the system maintains oxygen therapy effectiveness while eliminating the bulk and discomfort associated with separate conventional humidification systems. The integrated approach ensures both therapeutic effectiveness and subject comfort.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a portable, comfortable, and effective means of delivering high flow oxygen with increased humidity and positive expiratory pressure, improving ventilation and reducing discomfort for subjects with respiratory diseases.

Implementation Method 1

an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface via the second conduit to humidify the flow of concentrated oxygen containing gas

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS12285567B2High flow oxygen therapy with on-demand humidification and an active exhalation valve
Publication Date: 2025.04.29 KONINKLIJKE PHILIPS NV
  • US12285567B2 patent drawing
  • US12285567B2 patent drawing
  • US12285567B2 patent drawing

AI summary

The present disclosure pertains to a system for delivering a humidified flow of concentrated oxygen containing gas to a subject, the system comprising: a subject interface; an oxygen concentrator operatively coupled to the subject interface, the oxygen concentrator configured to provide a flow of concentrated oxygen containing gas to the subject interface via a first conduit; and an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface via the second conduit to humidify the flow of concentrated oxygen containing gas for delivery to the subject.