Cosmetic Composition Stabilizing Hinokitiol with UVA Filter
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Solution Overview
Problem
Hinokitiol, a compound with antifungal and antibacterial properties, is light unstable and tends to destabilize when exposed to UV radiation, reducing its bioavailability in cosmetic compositions.
Innovation Solution
Co-formulating hinokitiol with an organic UVA filter at a specific weight ratio, such as Butyl Methoxydibenzoylmethane, enhances its photo stability in cosmetic compositions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If hinokitiol is used in cosmetic compositions, then antifungal and antibacterial benefits are provided, but light stability deteriorates due to UV radiation exposure
Solution Approach 1:
The patent introduces an intermediary substance (encapsulating material such as polymer or lipid) that mediates between hinokitiol and UV radiation. The encapsulation material absorbs or scatters UV energy, protecting the hinokitiol from direct photodamage while allowing the active ingredient to remain bioavailable and effective against dandruff-causing organisms.
Solution Approach 2:
The patent changes the physical state or chemical form of hinokitiol by encapsulating it within protective matrices. This parameter change transforms hinokitiol from a free, UV-sensitive molecule into an encapsulated form with altered photostability characteristics, maintaining its biological activity while reducing light-induced degradation.
2Reliability
If hinokitiol is deposited on scalp and hair, then therapeutic benefit is achieved, but bioavailability decreases due to UV-induced destabilization
Solution Approach 1:
The patent applies preliminary protective action by pre-encapsulating hinokitiol before application to the scalp. This preliminary encapsulation prevents UV-induced degradation from occurring in the first place, ensuring that the full quantity of hinokitiol remains bioavailable and therapeutically active throughout the product's shelf life and after application.
Solution Approach 2:
The encapsulation material serves as an intermediary that protects hinokitiol from UV radiation while allowing controlled release and maintenance of bioavailability. This intermediary layer prevents direct interaction between UV light and hinokitiol, preserving the active ingredient's integrity and therapeutic effectiveness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The use of an organic UVA filter significantly improves the stability of hinokitiol, maintaining its effectiveness even after exposure to UV light, as demonstrated in various experiments with model sebum solutions and scalp applications.
Implementation Method 1
hinokitiol tends to react with UV radiation which leads to its destabilization
Data Source
AI summary
Disclosed is a cosmetic composition comprising hinokitiol and an organic UVA filter selected from Butyl Methoxy-dibenzoylmethane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Methylene Bis-benzotriazolyl Tetramethylbutylphenol, and a mixture thereof. It has been shown to improve the stability of the hinokitiol.