Hippocampus-amygdala transition area volume evaluation for emotional disorders
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Solution Overview
Problem
Existing methods for evaluating emotional disorders lack objectivity and reliability, particularly in determining the expression level of connective tissue growth factor (CTGF) in biological samples.
Innovation Solution
An emotional disorder evaluation system that acquires image data of the hippocampus and identifies volume data representing the volume of the right hippocampus-amygdala transition area, allowing for objective and reliable evaluation of emotional disorders.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If CTGF expression level detection is used to evaluate emotional disorders, then evaluation can be performed, but objectivity and reliability are insufficient
Solution Approach 1:
The patent changes the evaluation parameter from CTGF expression level (which showed insufficient reliability) to volume of the right hippocampus-amygdala transition area. This parameter change enables objective and reliable evaluation of emotional disorders by identifying significant volume differences between patients and healthy controls, thereby resolving the contradiction between evaluation capability and measurement precision.
2Measurement precision
If hippocampus image data is acquired and volume identification is performed, then objective and reliable evaluation is achieved, but measurement and detection difficulty increases
Solution Approach 1:
The patent extracts and focuses on a specific, well-defined region (the right hippocampus-amygdala transition area) from the complex hippocampal structure. By isolating this particular subregion for volume measurement, the system achieves objective and reliable evaluation while making the measurement process more manageable and less difficult compared to analyzing the entire hippocampus or other complex structures.
Data Source
AI summary
An emotional disorder evaluation system comprising: an acquisition unit configured to acquire image data representing the hippocampus of a subject, anda specification unit configured to identify volume data representing the volume of the right hippocampus-amygdala transition area of the subject in accordance with the image data.