His Bundle Capture Classification Using Frequency-Domain Signals

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Solution Overview

Problem

Existing cardiac stimulation devices struggle to identify and adjust to the minimum power and rate necessary for inducing His bundle capture and subsequent ventricular depolarization, particularly in cases of conduction disorders and dilated cardiomyopathy, leading to inefficient heart chamber synchronization.

Innovation Solution

A cardiac stimulation system that includes a lead for His bundle pacing and logic for automatically classifying responses to pacing impulses by analyzing frequency characteristics of the heart's electrical activity, using filters to modify and analyze frequency components, and adjusting impulse settings accordingly.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional cardiac stimulation devices are used to pace the ventricles, then ventricular pacing can be achieved, but hemodynamic efficiency is reduced due to non-physiological activation patterns and poor synchronization of heart chambers

Engineering Contradiction:
Improvehemodynamic efficiencyVSAvoidsynchronization of heart chambers
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent replaces conventional ventricular pacing (mechanical electrical stimulation) with His bundle pacing that utilizes the heart's natural conduction system. By delivering pacing impulses to the His bundle rather than directly to the ventricular myocardium, the system restores physiological activation patterns through the natural His-Purkinje network, thereby improving hemodynamic efficiency and chamber synchronization without requiring complex mechanical adjustment systems.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the pacing location parameter from ventricular myocardium to His bundle tissue. This parameter change enables utilization of the fast-conducting His-Purkinje system, resulting in physiological ventricular activation patterns similar to normal sinus rhythm, thereby improving hemodynamic efficiency while maintaining ease of operation through automated detection and classification.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If automated classification logic is implemented to identify capture types, then precision in identifying His bundle capture is improved, but device complexity increases

Engineering Contradiction:
Improveidentification of capture typesVSAvoidclassification logic
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent utilizes frequency domain analysis of electrical signals to classify capture types. By transforming time-domain electrogram signals into frequency-domain representations and analyzing specific frequency characteristics (such as dominant frequencies and spectral patterns), the system achieves precise identification of selective versus non-selective His bundle capture. This signal processing approach provides high measurement precision while keeping the classification logic relatively simple and computationally efficient.

Inventive Principle:
Principle #18Mechanical vibration

Data Source

PatentUS12521557B2Frequency domain-based methods for his bundle capture classification
Publication Date: 2026.01.13 PACESETTER INC
  • US12521557B2 patent drawing
  • US12521557B2 patent drawing
  • US12521557B2 patent drawing

AI summary

Systems and methods for His bundle pacing and classifying response to pacing impulses include applying, using a pulse generator, an impulse through a stimulating electrode to induce a response from a patient heart. A response to the impulse is measured using at least one sensing electrode and frequency characteristics of the response are analyzed to determine whether His bundle capture has occurred and, if so, what type of capture has occurred. To facilitate analysis, the response measured from the patient heart may also be filtered to pass or stop frequencies indicative of certain capture types.