Histological Sample Purifying Device Gas Flow Reagent Removal
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Solution Overview
Problem
Existing apparatuses for working on histological samples contaminate and deplete reagent containers quickly due to residual reagents adhering to samples or sample holding arrangements, leading to increased operational expenses.
Innovation Solution
An apparatus equipped with a purifying device that uses a gas flow to blow off or suck away reagents from samples and sample holding arrangements, preventing contamination of subsequent reagent containers and reducing the need for frequent reagent replacement, with adjustable parameters for optimal reagent removal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If samples and sample holding arrangements are withdrawn from reagent containers without purification, then sample processing is simple and fast, but reagent containers are quickly contaminated and depleted requiring frequent replacement
Solution Approach 1:
The purifying device is positioned to blow off reagents from samples and sample holding arrangements immediately upon withdrawal from reagent containers, before they can contaminate subsequent containers. This preliminary purification action prevents reagent mixing and depletion, extending reagent life without slowing down the automated sample processing workflow
Solution Approach 2:
A gas flow is introduced as an intermediary medium between the reagent liquid and the samples/holding arrangements. The gas flow selectively removes excess reagent from sample surfaces without affecting the reagent in containers, acting as a mediator that transfers reagent from samples back to containers or to a collection system, preventing contamination while maintaining processing efficiency
2Reliability
If reagent containers are frequently monitored and maintained, then reagent contamination is prevented, but operational time and costs increase
Solution Approach 1:
The purifying device operates automatically in the sample processing path, performing self-service purification of samples and holding arrangements without requiring manual intervention. The system self-regulates reagent removal and prevents contamination proactively, eliminating the need for frequent manual monitoring and maintenance of reagent containers while ensuring continuous reagent purity
Solution Approach 2:
The system incorporates sensors that detect reagent levels and contamination states in real-time, providing feedback to the control system. This enables automatic adjustment of purification parameters and timely refilling or replacement of reagent containers, maintaining high reagent purity while minimizing manual intervention and operational downtime
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The purifying device effectively prevents reagent contamination and prolongs the replacement interval of reagents, reducing operational costs and ensuring efficient sample processing by ensuring reagents are not introduced into subsequent containers, thereby enhancing the histological sample processing workflow.
Implementation Method 1
which by means of a gas flow blows off at least a part of the reagent adhering to the sample and/or the sample holding arrangement
Implementation Method 2
Alternatively, the purifying device sucks away at least a part of the reagent adhering to the sample and/or the sample holding arrangement
Data Source
AI summary
The invention relates to an apparatus for treatment of histological samples. The apparatus includes at least a working station, in which the sample gets into contact with a liquid reagent. Further, the apparatus includes a purification device, which blows off at least a part of the reagent adhering to the sample and/or the sample holding arrangement by means of a gas flow, or which sucks off at least a part of the reagent adhering to the sample and/or a sample holding arrangement.