Histology Sample Storage Cell With Automated Cassette Traceability
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Solution Overview
Problem
Existing storage systems for histological samples in anatomical pathology laboratories lack full automation, traceability, flexibility, and efficient integration with various transport systems, leading to potential human errors and inefficiencies.
Innovation Solution
A storage system with an input/output module and a storage cell that uses manipulator devices for automated handling of cassettes, incorporating optical and RFID identification, enabling seamless integration with pneumatic and AMR transport systems, and allowing both automated and manual operations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Extent of automation
If manual handling of histological samples is used, then flexibility and ease of operation are maintained, but human errors increase and automation level decreases
Solution Approach 1:
The system enables self-service through automated manipulator devices that independently handle cassettes and blocks without human intervention. The input/output module automatically receives and dispenses cassettes, while manipulator devices autonomously transfer blocks between storage positions and transport systems, eliminating human error in sample handling.
Solution Approach 2:
Manual mechanical handling is replaced with automated manipulator devices equipped with sensors and control systems. These devices use optical codes and RFID tags to identify samples and automatically execute transfer operations, substituting human mechanical actions with programmable robotic systems that maintain precision and reliability.
2Productivity
If automated handling systems are implemented, then productivity and efficiency increase, but device complexity increases
Solution Approach 1:
The system is divided into modular functional units: an input/output module for cassette handling, multiple independent manipulator devices for block transfer, and integration points with transport systems. Each manipulator device operates as an independent module with its own sensors and actuators, allowing the system to achieve high productivity through parallel operations while managing complexity through modular architecture.
Solution Approach 2:
The manipulator devices are designed with universal capabilities to handle different block sizes and positions, and the input/output module can interface with various transport systems (pneumatic, AMR, conveyor). This multi-functionality allows a single automated handling system to serve multiple purposes and integrate with existing laboratory infrastructure, improving productivity without proportionally increasing complexity.
3Loss of information
If full automation is implemented, then traceability and reliability improve, but cost and device complexity increase
Solution Approach 1:
The system implements feedback through optical code readers and RFID scanners that continuously monitor sample identification and position. Sensors detect when cassettes are received and blocks are transferred, providing real-time feedback to the control system. This feedback mechanism ensures complete traceability by recording every action and position change, while the automated feedback loops simplify data management compared to manual tracking systems.
4Adaptability or versatility
If integration with multiple transport systems is enabled, then adaptability and versatility improve, but device complexity and difficulty of integration increase
Solution Approach 1:
The input/output module is designed with universal interfaces that can accommodate different transport system protocols and physical configurations. The manipulator devices can interface with pneumatic tubes, autonomous mobile robots (AMR), conveyor belts, and manual transfer points through standardized communication and mechanical interfaces. This universality allows the system to adapt to various transport configurations without requiring custom integration for each system type.
Solution Approach 2:
The input/output module serves as an intermediary between the automated handling system and various transport systems. It provides a standardized interface that translates between different transport protocols and physical formats, absorbing the complexity of integration while presenting a simplified interface to the manipulator devices. This intermediary layer enables adaptability to multiple transport systems without increasing the complexity of the core handling functionality.
Data Source
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AI summary
A system (1) for the storage of blocks (B) of embedding material containing histological samples, comprising a controlled atmosphere storage cell (2), wherein a plurality of compartments (12) is arranged to receive trays (13) each having an identification element. Each tray (13) carries a plurality of cassettes (14) each carrying a block (B) containing a histological sample. Each cassette (14) bears an identification element (48). The position of each cassette in a tray (13) is stored and the position of each tray (13) in the storage cell (2) is stored. The system comprises an input/output module (3) with a plurality of input stations (24) and at least one output station (60). The input stations (24) comprise at least a first input station (24) associated to an interface station (46) with an automatic transport system of cassettes (14). The output station (60) can be configured to interface with a structure (62) for manual loading or unloading of trays (13) carrying cassettes (14), or to cooperate with an autonomous mobile robot configured to support one or more trays (13) carrying cassettes (14).