Holy Basil Extract for Skin Anti-Aging and Inflammation
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Solution Overview
Problem
Current cosmetic, pharmaceutical, and dermatological products lack effective solutions for addressing skin, mucous membrane, and vascular disorders, particularly in preventing or treating inflammatory reactions, oxidative stress, and aging, while also maintaining skin homeostasis and microbiota balance.
Innovation Solution
A polyphenol-rich extract from the aerial parts of holy basil (Ocimum sanctum), specifically obtained through a solid/liquid extraction method using water or glycols, is used in compositions for topical application to provide antioxidant, anti-inflammatory, and anti-aging benefits, improving skin and mucous membrane health.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cosmetic and pharmaceutical products are used, then basic skin care functions are provided, but they lack effective solutions for addressing inflammatory reactions, oxidative stress, and aging
Solution Approach 1:
The holy basil extract is designed to perform multiple functions simultaneously: antioxidant protection against oxidative stress, anti-inflammatory action to reduce inflammatory reactions, and anti-aging effects to prevent skin aging. This multi-functional approach allows a single composition to address various skin conditions including inflammatory disorders, oxidative damage, and aging signs, thereby resolving the contradiction between reliability and adaptability.
2Reliability
If polyphenol-rich extract is used to provide antioxidant and anti-inflammatory benefits, then skin protection and healing are improved, but the extraction process complexity increases
Solution Approach 1:
The extraction process utilizes parameter changes including temperature control (60-80°C), pH adjustment (pH 2-4), and solvent selection (aqueous or alcoholic) to optimize polyphenol extraction from holy basil. By systematically adjusting these parameters, the method achieves high polyphenol content (at least 6% by weight) while maintaining a relatively simple extraction procedure, thus resolving the contradiction between reliability and device complexity.
3Reliability
If holy basil extract is used to stimulate dermal matrix markers and improve skin elasticity, then anti-aging effects are enhanced, but the concentration and purity requirements increase
Solution Approach 1:
The invention extracts and concentrates the active polyphenolic compounds from holy basil aerial parts through a systematic extraction process. This extraction isolates the bioactive components responsible for stimulating dermal matrix markers and improving skin elasticity, achieving at least 6% polyphenol content by weight. The concentration and purification steps ensure sufficient manufacturing precision while maintaining reliable anti-aging effects.
4Adaptability or versatility
If conventional products are used to maintain skin homeostasis and microbiota balance, then basic skin health is preserved, but they lack effective solutions for specific skin disorders
Solution Approach 1:
The holy basil extract composition provides localized therapeutic effects tailored to specific skin conditions through its distinct polyphenolic profile. The extract demonstrates specific anti-inflammatory activity for inflammatory disorders, antioxidant protection for oxidative stress damage, and anti-aging effects for aging signs. This localized quality approach allows the same composition to effectively address multiple specific skin disorders while maintaining skin homeostasis and microbiota balance.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The holy basil extract demonstrates significant antioxidant and anti-inflammatory activities, inhibiting ROS production, lipid peroxidation, and IL-8 production, while stimulating dermal matrix markers and improving skin elasticity, effectively addressing various skin and mucous membrane disorders and aging.
Implementation Method 1
The holy basil extract demonstrates significant antioxidant and anti-inflammatory activities, inhibiting ROS production, lipid peroxidation
Implementation Method 2
The holy basil extract demonstrates significant antioxidant and anti-inflammatory activities, inhibiting ROS production, lipid peroxidation, and IL-8 production
Data Source
AI summary
The invention relates to an extract of top growth of holy basil, in particular of Ocimum sanctum, a method for preparing the extract, and the extract obtainable by said method. The invention also relates to a composition comprising such an extract, the composition advantageously being a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or the skin appendages, and for use in preventing or treating vascular disorders. Finallyc the invention relates to a cosmetic care method for the skin, skin appendages or mucous membranes, with a view to improving the condition or appearance thereof, which method consists in administering such a composition or such an extract.