Home Medicament Proportioning With Purified Water Feedback Control

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Solution Overview

Problem

Current medical fluid preparation systems for home use are complex, costly, and require high precision, making them difficult to install and maintain, especially for home-based blood treatments, which often lack the safety and efficacy of clinic settings due to the need for purified water and specialized equipment.

Innovation Solution

A compact medicament preparation system combining a water purification module and a medicament proportioning module, which uses replaceable tagged components with data carriers for safety and maintenance tracking, and a cycler for on-demand fluid preparation, allowing for safe and reliable operation in home or critical care environments without the need for large infrastructure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If large reverse osmosis plants are used for water purification in home settings, then purified water supply is achieved, but system complexity and installation difficulty increase significantly

Engineering Contradiction:
Improvepurified water supplyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system is divided into separate functional modules: a water purification module that can be integrated with existing household plumbing, and a medicament proportioning module. This segmentation allows the purification function to be achieved without requiring a complete large-scale reverse osmosis plant in the home.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The water purification module is designed to work with existing household water infrastructure, allowing it to serve multiple purposes (general water purification and medicament preparation) without requiring dedicated large-scale equipment.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If clinic-grade medicament preparation systems are deployed at home, then treatment safety and efficacy are improved, but installation cost and maintenance complexity increase

Engineering Contradiction:
Improvetreatment safetyVSAvoidinstallation cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The system employs disposable fluid circuits and replaceable tagged components that can be pre-packaged and sterilized. This eliminates the need for complex sterilization infrastructure at the home location while maintaining treatment safety, and reduces installation costs by using simple connection mechanisms.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The system includes automated monitoring and control features that reduce the need for professional maintenance. Sensors track fluid levels, contamination, and operational parameters, allowing the system to self-diagnose and alert users when service is needed.

Inventive Principle:
Principle #25Self-service

3Manufacturing precision

If precise medicament proportioning is achieved in home settings, then treatment quality is improved, but device complexity and training requirements increase

Engineering Contradiction:
Improvemedicament mixture precisionVSAvoidoperation simplicity
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The system replaces manual mixing operations with automated electronic proportioning mechanisms. Pumps and valves controlled by microprocessors precisely meter the addition of medicament components to water, eliminating the need for manual measurement and mixing while ensuring consistent precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system incorporates sensors that monitor fluid flow rates, pressure, and temperature in real-time. This feedback is used by the control system to adjust proportioning parameters dynamically, ensuring precise medicament preparation even as operating conditions change during treatment.

Inventive Principle:
Principle #23Feedback

4Reliability

If replaceable tagged components with data carriers are used, then safety and maintenance tracking are improved, but device complexity increases

Engineering Contradiction:
Improvesafety trackingVSAvoidcomponent complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Data carriers serve as intermediaries between the physical components and the system's control logic. These tags store identification and status information that can be automatically read by the system, enabling safety tracking and maintenance scheduling without requiring complex embedded electronics in each component.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a safe, reliable, and compact solution for medical fluid preparation, enabling effective and efficient home-based medical treatments by ensuring the quality and precision of medicaments, reducing the complexity and cost of installation and maintenance, and eliminating the need for large-scale water purification systems.

Implementation Method 1

water purification module

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

medicament proportioning module which mixes water and medicament concentrate in a predefined proportion to generate medicament

Methodology Applied
Scientific EffectMixing: Stirring

Data Source

PatentUS11986582B2Medicament preparation and treatment devices, methods, and systems
Publication Date: 2024.05.21 NXSTAGE MEDICAL INC
  • US11986582B2 patent drawing
  • US11986582B2 patent drawing
  • US11986582B2 patent drawing

AI summary

A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.