Homeopathic Wound Composition Modulating Macrophage Infiltration

Solution Overview

Problem

There is a need for effective compositions and methods to facilitate wound healing that do not interfere with the natural inflammatory response and can enhance the wound healing process without adverse effects, as conventional medications can delay healing and herbal remedies' mechanisms are not fully understood.

Innovation Solution

A composition comprising Aranea diadematus, Calcium phosphoricum, Equisetum hiemale, Ferrum jodatum, Fumaria officinalis, Gentiana lutea, Geranium robertianum, Levothyroxinum, Myosotis arvensis, Nasturtium officinale, Natrium sulfuricum, Pinus silvestris, Sarsaparillae radix, Scrophularia nodosa, Teucrium scorodonia, and Veronica officinalis in specific homeopathic dilutions, which modulates inflammatory mechanisms and promotes wound healing by influencing immune cell infiltration and cytokine secretion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional medications are used to treat wounds, then wound healing may be delayed, but they provide immediate therapeutic intervention

Engineering Contradiction:
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent extracts and eliminates harmful components from conventional wound treatments by using only homeopathic dilutions (typically 6CH or higher) of active ingredients. This extraction approach removes toxic effects while preserving the therapeutic benefit of influencing wound healing processes through modulated immune response and reduced inflammation.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent fundamentally changes the concentration parameter of active ingredients from conventional therapeutic doses to homeopathic dilutions (6CH or higher). This parameter transformation eliminates harmful effects while maintaining therapeutic efficacy by working with the body's natural healing processes rather than forcing external intervention.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If herbal remedies are used to support wound healing, then natural healing processes are enhanced, but the mechanism of action remains unclear

Engineering Contradiction:
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The patent incorporates feedback mechanisms by selecting homeopathic ingredients specifically known to influence inflammatory responses and wound healing processes. The composition includes ingredients like Calendula officinalis (anti-inflammatory), Arnica montana (edema reduction), and Hepar sulfuris (infection control), which provide feedback loops that modulate the body's natural healing response based on the wound's specific needs at different stages.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent creates a universal wound healing composition that addresses multiple aspects of wound management simultaneously. The homeopathic mixture tackles inflammation, edema, infection risk, and tissue regeneration through a single multi-functional treatment, eliminating the need for separate interventions for each healing aspect while providing comprehensive support.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If anti-inflammatory drugs are used to reduce inflammation, then inflammatory response is dampened, but wound healing is delayed

Engineering Contradiction:
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent applies partial action by using homeopathic dilutions (6CH or higher) of anti-inflammatory ingredients like Calendula officinalis and Arnica montana. These diluted forms provide sufficient anti-inflammatory effect to reduce harmful inflammation without exceeding the threshold that would suppress necessary inflammatory responses required for proper wound healing.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

Instead of using conventional anti-inflammatory drugs that suppress the inflammatory response, the patent inverts the approach by using homeopathic ingredients that modulate and balance inflammation. Ingredients like Hepar sulfuris and Calendula officinalis in homeopathic dilutions promote healthy inflammatory processes while preventing excessive or harmful inflammation, effectively doing the opposite of suppression.

Inventive Principle:
Principle #13The other way round (Inversion)

Data Source

PatentEP2863931B1Compositions for use in treating wounds
Publication Date: 2017.11.15
  • EP2863931B1 patent drawingFigure 1A~1C
  • EP2863931B1 patent drawingFigure 2A~2C
  • EP2863931B1 patent drawingFigure 3A~3E

AI summary

The present invention is concerned with plant and animal derived pharmaceutically useful compositions. In particular, it relates to a composition for use in treating wound healing, wherein said composition comprises Aranea diadematus, Calcium phosphoricum, Equisetum hiemale, Ferrum jodatum, Fumaria officinalis, Gentiana lutea, Geranium robertianum, Levothyroxinum, Myosotis arvensis, Nasturtium officinale, Natrium sulfuricum, Pinus silvestris, Sarsaparillae radix, Scrophularia nodosa, Teucrium scorodonia, and Veronica officinalis. Contemplated is also a medicament comprising said composition as well as a method for treating wound healing in a subject suffering therefrom, said method comprises administering in a therapeutically effective amount to the said subject a composition.